Funded DPhil/PhD in Therapeutic Genomics at the University of Oxford and Newcastle University University of Oxford in United Kingdom

Department of Pathology, University of Cambridge is advertising a fully funded PhD studentship in the lab of Professor Heike Laman . The project investigates how ubiquitin regulates secretory trafficking in dopaminergic neurons , with a focus on how the E3 ubiquitin ligase subunit FBXO7 controls protein movement through the secretory pathway. The research uses human stem cell-derived neurons as a model system and combines live-cell imaging , RUSH assays , proteomics , and functional experiments....

Postdoctoral opening at the University of Padova in the HSC Gene Therapy Laboratory , Istituto di Ricerca Pediatrica, Department of Women’s and Children’s Health. The project focuses on HSC gene therapy for Mevalonate Kinase Deficiency (MKD) , including development and preclinical validation of an autologous hematopoietic stem cell gene therapy approach for a rare autoinflammatory disease caused by MVK variants . Research activities include restoring MVK function in patient-derived hematopoietic...

PhD opportunity at the University of St Andrews in the School of Psychology and Neuroscience on descending and ascending control of locomotor and respiratory central pattern generators (CPGs) in health and disease . This project sits at the intersection of neuroscience , neurology , cell biology , and molecular biology , with a strong focus on motor control, respiratory control, and disease-relevant circuit mechanisms. The research will investigate how supraspinal descending pathways and ascendi...

PhD opportunity: Lysosomal TMEM106B in brain ageing and disease at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, Cambridge, United Kingdom. This project with Dr Diana Arseni explores how the lysosomal protein TMEM106B forms amyloids in the brain in an age-dependent manner and how TMEM106B genetic variants may influence healthy ageing and disease risk in frontotemporal lobar degeneration and Alzheimer’s disease . The research is centered on lysosomal biology , brain a...

PhD opportunity at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom on structural and cellular approaches to understand microtubule motors . This project sits at the intersection of cell biology , molecular biology , and structural biology , with a strong focus on microtubule motors such as dynein and kinesin . The research asks how motors are linked to cargos and coordinated to deliver organelles, RNAs, and proteins to the correct destination, especially...