PhD in Structural and Cellular Approaches to Understand Microtubule Motors Medical Research Council Laboratory of Molecular Biology in United Kingdom

PhD opportunity: Lysosomal TMEM106B in brain ageing and disease at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, Cambridge, United Kingdom. This project with Dr Diana Arseni explores how the lysosomal protein TMEM106B forms amyloids in the brain in an age-dependent manner and how TMEM106B genetic variants may influence healthy ageing and disease risk in frontotemporal lobar degeneration and Alzheimer’s disease . The research is centered on lysosomal biology , brain a...

PhD opportunity in pathological protein assembly in neurodegenerative diseases at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom . The project is centered on the molecular pathology of neurodegeneration, with a focus on amyloid filament formation by disease-associated proteins such as TDP-43 , annexin A11 , and TAF15 . Two PhD project directions are described. One aims to reproduce pathological protein filament structures in vitro using protein biochemist...

PhD opportunity in AMPA receptor structure and function at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom . This project sits at the intersection of neuroscience , molecular biology , and structural biology , focusing on how AMPA glutamate receptors (AMPA-Rs) and their auxiliary proteins shape excitatory synaptic transmission, plasticity, and information storage in the brain. The lab aims to decode AMPAR signalling complexity from atomic structure...

PhD opportunity at the University of St Andrews in the School of Psychology and Neuroscience on descending and ascending control of locomotor and respiratory central pattern generators (CPGs) in health and disease . This project sits at the intersection of neuroscience , neurology , cell biology , and molecular biology , with a strong focus on motor control, respiratory control, and disease-relevant circuit mechanisms. The research will investigate how supraspinal descending pathways and ascendi...

The MRC Laboratory of Molecular Biology (LMB) in Cambridge is accepting applications for its 2027 PhD programme , with students starting in October 2027 . The programme is registered through the University of Cambridge and is a four-year, full-time PhD that places students in individual LMB research groups. Research areas mentioned include molecular biology , structural biology , cell biology , neurobiology , protein and nucleic acid chemistry , and related biomedical sciences . Applicants can c...