Medical Research Council (Cambridge)
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PhD in Lysosomal TMEM106B in Brain Ageing and Disease Medical Research Council (Cambridge) Laboratory of Molecular Biology in United Kingdom
Degree Level
PhD
Field of study
Cell Biology
Funding
Competition funded PhD project for students worldwide. Funding details are not specified in the post beyond being funded.
Deadline
Dec 8, 2026
Country
United Kingdom
University
Medical Research Council (Cambridge)

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About this position
PhD opportunity: Lysosomal TMEM106B in brain ageing and disease at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, Cambridge, United Kingdom.
This project with Dr Diana Arseni explores how the lysosomal protein TMEM106B forms amyloids in the brain in an age-dependent manner and how TMEM106B genetic variants may influence healthy ageing and disease risk in frontotemporal lobar degeneration and Alzheimer’s disease.
The research is centered on lysosomal biology, brain ageing, neurodegeneration, cell biology, molecular biology, and structural biology. The project will use multidisciplinary approaches and may involve cell biology, structural, and biochemical models of ageing and neurodegeneration. The student’s interests are expected to help shape the direction of the project.
This is a competition funded PhD project and is open to students worldwide. The post does not specify stipend amount, tuition coverage, or additional financial details.
Applicants interested in the project should register their interest via the FindAPhD page. The university will respond directly. For further information, prospective applicants are strongly encouraged to contact Dr Diana Arseni at [email protected].
Application / enquiry link: the FindAPhD project page.
Funding details
Competition funded PhD project for students worldwide. Funding details are not specified in the post beyond being funded.
What's required
Applicants should have strong interest in the project area and be willing to contribute to the direction of the research. The project uses multidisciplinary approaches and available projects will utilise cell biology, structural, and biochemical models of ageing and neurodegeneration. Contact with the supervisor is strongly encouraged for further information.
How to apply
Register your interest through the FindAPhD page. The university will respond directly. For project-specific questions, contact Dr Diana Arseni by email.
More information can be found here
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