Metabolism and prostate cancer plasticity Helmholtz Zentrum Munich in Germany

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.This is what drives us. Why not join us and make a difference?The Institute for Diabetes and Cancer, member of the Helmholtz Diabetes Center and the German Center for Diabetes Research aims at identifying common molecular targets in order to develop personalized therapies for Metabolic and Tumor diseases. We invite applications for a fully funded PhD candidate position at the Metabolic Dysfunction and Cancer Division starting October 2024, to study metabolic control of prostate cancer plasticity. Through this project, the candidate will unravel and interrogate the unique metabolic features of highly plastic prostatic tumors with the ultimate goal of developing innovative therapeutic strategies for this lethal disease.Your tasksConduct experimental research using advanced tools and techniques including genetic mouse models, organoids, and single-cell transcriptomics.Analyze and interpret data obtained from in-vivo and in-vitro experiments.Collaborate with an international and interdisciplinary research team to integrate findings and contribute to publications in high-ranking journals.Present research findings at national and international scientific meetings.Your profileExceptional students holding a Master’s degree in a relevant field.Strong interest in cancer and metabolism research.Demonstrable experience in molecular biology techniques, animal models, or analysis of OMICS datasets.Documented experience (FELASA B certificate) in mouse handling, breeding and experimentation is highly desired, but not mandatory.Outstanding motivation to participate in a competitive research program.Excellent English language proficiency, both written and spoken. BenefitsCareer counseling: Career Center for PhD candidatesHealth Promotion: Sports, company doctor, mental health initiativesInternational Staff Service: Support with the relocation and integration process in GermanyScientific Resources: State-of-the-art infrastruture and Core FacilitiesScientific Training: Helmholtz Munich Graduate SchoolWork-Life-Balance: Flexible working hours and flexi-time modelsRecreation: 30 days annual leave, flexi days, plus public holidaysRetirement Provision: Company pension planThis position provides the opportunity for you to build specialist knowledge whilst developing key professional experience, both of which will help you to make strides in your scientific career.Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees at Federal Level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of receiving an allowance if the applicable conditions are met. The position has an (initial) fixed term of three years but may be extended under certain circumstances.We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference. If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree. Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.Interested in applying?If you have any questions, feel free to contact Miriam Guhl, +49 (0)89 3187-1046, who will be happy to help.Your application should includeCVCover letterDegrees/Diplomas/CertificatesReferences from recent employersContact details for at least two referees