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Instituto de Investigação e Inovação em Saúde da Universidade do Porto

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PhD Holder Researcher in Neuroscience and Neuroengineering Instituto de Investigação e Inovação em Saúde da Universidade do Porto in Portugal

Degree Level

PhD

Field of study

Computer Science

Funding

Available

Deadline

Nov 29, 2026

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Country

Portugal

University

Instituto de Investigação e Inovação em Saúde da Universidade do Porto

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Keywords

Computer Science
Biomedical Engineering
Biology
Microscopy
Python Programming
Neuropsychology
Neuroinformatics
Glioblastoma
Neuroengineering
Bioanalysis

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About this position

PhD-holder researcher position in Neuroscience and Neuroengineering at the Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) in Porto, Portugal. The project, LOCALISE (Loco-radiolysed multi-modal treatment for glioblastoma self-enhanced chemotherapy and targeted RNA delivery), sits at the intersection of neural science, imaging, and translational bioengineering.

The selected researcher will join the Neuroengineering and Computational Neuroscience group at i3S and contribute to experimental work centered on advanced microscopy for cell-culture studies. The project focuses on quantifying therapeutic effects through viability assays and longitudinal live-cell fluorescence imaging, as well as assessing functional biocompatibility by calcium imaging in neural cultures exposed to selected hydrogel formulations. The research is explicitly aimed at understanding how these multimodal treatments interact with neural systems and how imaging can be used to characterize those effects in detail.

The position is embedded in a research environment at i3S, a health and innovation institute associated with the University of Porto, with work carried out in Porto under a full-time research contract. The announcement names Paulo Aguiar as chair of the jury, with Marina Silva, José Mateus, and substitute Rita Ribeiro as members.

The advert emphasizes hands-on experimental and analytical research using microscopy-based workflows, automated image acquisition, and neuronal culture systems. The role is suited to a researcher with strong experience in bioimage analysis, neural activity assessment, and computational tools for imaging and data handling.

Funding details

Available

What's required

PhD degree in Neuroscience, Neurobiology, Neuroengineering or related areas is required. The candidate should have expertise in advanced fluorescence/confocal microscopy and quantitative image analysis, ideally for inflammatory responses and cell death; proven experience developing bioimage analysis pipelines, including scripts and macros in ImageJ, with prior morphometric analysis; proficiency with Micro-Manager, including creating novel configurations; experience with automated image acquisition, camera APIs, and acquisition protocols; prior work with neuronal cultures and assessment of neuronal activity and viability; experience with Python, MATLAB, and development of graphical user interfaces; strong analytical skills, critical thinking, problem-solving ability, and excellent oral and written English.

How to apply

Prepare the required documents: copy of PhD certificate or diploma, detailed CV, and motivation letter. Submit the application digitally in PDF format through the provided online application link between 2026-11-16 and 2026-11-29. Candidates are notified by email after the selection process.

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