Publisher
source

University of Dundee

PhD in Plant Stress Responses, Cereblon E3 Ubiquitin Ligase, and Targeted Protein Degradation University of Dundee in United Kingdom

Degree Level

PhD

Field of study

Molecular Biology

Funding

This is a 4-year funded PhD project supported by the EastBio BBSRC Doctoral Landscape Award. Funding covers a stipend at the UKRI standard rate and UK-level tuition fees; the University of Dundee will cover the Home-International fee difference. A mandatory training programme and a 3-month placement are included.

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United Kingdom

University

University of Dundee

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Keywords

Molecular Biology
Biology
Protein Chemistry
Plant Physiology
Chemical Biology
Heat Stress

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About this position

PhD opportunity at the University of Dundee in plant biology, stress physiology, molecular biology, chemical biology, proteomics, and targeted protein degradation.

This EASTBIO/BBSRC-funded doctoral project investigates how Cereblon E3 ubiquitin ligase functions during environmental stress responses in plants, especially heat stress, and how Cereblon could be used in targeted protein degradation (TPD) approaches such as PROTAC-like strategies. The project explores plant proteome remodeling, ubiquitination, protein turnover, and the role of Cereblon in adapting to temperature stress.

The research team will provide training in plant temperature physiology and development, molecular biology, chemical biology, targeted protein degradation, protein biochemistry, proteome enrichment, proteomics, and western blotting. The project is co-designed with the successful applicant, making it suitable for candidates interested in shaping the direction of the research.

Funding: 4-year funded PhD studentship via the EastBio BBSRC Doctoral Landscape Award. Funding includes a stipend at the UKRI standard rate and UK tuition fees; the University of Dundee covers the Home-International fee difference.

Eligibility: Open to UK and international students. The post is advertised as a competition-funded PhD project.

How to apply: Visit the University of Dundee EASTBIO Doctoral Training Partnership programme page for full application instructions and submit through the university route.

Funding details

This is a 4-year funded PhD project supported by the EastBio BBSRC Doctoral Landscape Award. Funding covers a stipend at the UKRI standard rate and UK-level tuition fees; the University of Dundee will cover the Home-International fee difference. A mandatory training programme and a 3-month placement are included.

What's required

Applicants should be talented individuals interested in plant temperature physiology and development, molecular biology, chemical biology, targeted protein degradation, and protein biochemistry. The project will particularly involve proteome enrichment approaches, proteomics, western blotting, protein substrate selection, ubiquitination, and degradation. The studentship is open to UK and international students.

How to apply

See the University of Dundee programme page for the BBSRC EASTBIO Doctoral Training Partnership (DTP) Studentship and apply through the university application route. Review the programme information before submitting your application.

More information can be found here

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