International PhD Programme (IPP) Mainz, Institute of Molecular Biology
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PhD Position: Deciphering the role of the BAF-associated ARID proteins in colorectal cancer (m/f/d) International PhD Programme (IPP) Mainz in Germany
Degree Level
PhD
Field of study
Cancer Biology
Funding
Available
Deadline
Oct 15, 2026
Country
Germany
University
International PhD Programme (IPP) Mainz, Institute of Molecular Biology
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About this position
The International PhD Programme (IPP) Mainz is offering a fully funded PhD position at the Institute of Molecular Biology in Mainz, Germany, in the research group of Sandra Schick. The project is part of an interdisciplinary and international environment, with English as the working language, and gives the successful candidate access to advanced scientific training, professional skills development, and state-of-the-art core facilities.
Project topic: Deciphering the role of the BAF-associated ARID proteins in colorectal cancer, with a focus on DNA mismatch repair and cell cycle control. The project investigates how loss of ARID subtype-determining subunits affects genome maintenance, microsatellite instability, and cellular response pathways in colorectal cancer. Previous findings suggest distinct vulnerabilities and resistances after ARID loss, motivating deeper mechanistic studies of ARID function in cancer.
Research approach: The PhD candidate will work with CRISPR-engineered cancer cell lines and colon organoid cultures and will use bulk and single-cell NGS, proteomics, genome engineering, compound screening, and microscopy. The project is carried out in collaboration with the Luck lab, which contributes a structural proteomics perspective. The research is embedded in the collaborative research consortium SFB1361, pending a funding decision in November 2026.
Eligibility highlights: Applicants should hold a Master’s degree or equivalent, have a good command of English, and provide two letters of reference. The programme highlights an ambitious and interactive personality and a strong interest in multidisciplinary research.
Funding and conditions: The position is fully funded until completion of the thesis. It is a full-time, temporary PhD position in Mainz, Germany.
Application window: The deadline for applications is 15 October 2026 at 12:00 (Europe/Berlin). Interviews will take place at IMB in Mainz on 18–19 January 2027, and the expected starting date is between 1 February and 31 July 2027.
How to apply: Submit the application through the IPP online form and select “Schick (BAF)” as the group preference. The position announcement directs applicants to the IPP application platform for further details.
Funding details
Available
What's required
Master’s degree or equivalent in a relevant field; good command of English; two letters of reference; applicants should be an ambitious scientist with an interactive personality. The research field is biological sciences and the position is at first-stage researcher level.
How to apply
Apply via the IPP online form at https://www.imb.de/phd/apply and select Schick (BAF) as the group preference. Submit the application before 15 October 2026; interviews are scheduled at IMB in Mainz on 18–19 January 2027.
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