Meet ApplyKite Twin, the application assistant that learns with you
Meet your Twin, it learns with you
Your Twin learns with you
Launch week codes:30% off annual Pro20% off monthly Pro
Ends in00h00m00s
Ends in00h00m00s
Roger Schibli
3 months ago
This position has expired. You can find similar positions from the section below or browse our positions listing pages.
PhD Position in Radiopharmaceutical Sciences: Glycoengineered Peptides and Nanobodies for Imaging and Therapy ETH Zürich in Switzerland
Degree Level
PhD
Field of study
Chemistry
Funding
Available
Country
Switzerland
University
ETH Zürich
Suggested positions
Keywords
About this position
ETH Zurich and the Paul Scherrer Institute are offering a funded PhD position in radiopharmaceutical sciences within the Center for Radiopharmaceutical Sciences (CRS), a joint research center internationally recognized for pioneering work in radiopharmaceutical chemistry and targeted radionuclide therapy.
The project is hosted by the Schibli Group, led by Prof. Roger Schibli, in close collaboration with the laboratory of Prof. Kaspar Locher in the Department of Biology at ETH Zurich. The research focuses on glycoengineered peptides and nanobodies for imaging and therapy, with an emphasis on understanding how defined N-glycosylation can improve pharmacokinetic and pharmacological behavior. This is a translational project connecting glycobiology, molecular imaging, radiochemistry, and preclinical evaluation.
As a PhD student, you will develop and optimize radiolabeling strategies for glycosylated peptides and nanobodies, perform quality control and analytical characterization, conduct cell-based binding and uptake studies, and plan and analyze biodistribution, PET, and SPECT imaging in mouse models. You will also investigate pharmacokinetic and pharmacodynamic properties of novel radiolabeled compounds and collaborate closely with a PhD student in the Locher laboratory to optimize glycosylated constructs.
The position is well suited to candidates with a strong background in chemistry, pharmaceutical sciences, biochemistry, molecular biology, or biotechnology, and with interest or experience in radiopharmaceutical sciences, radiochemistry, bioconjugation, protein engineering, cell biology, or preclinical imaging. Experience with PET/SPECT imaging, radiopharmacy, or animal studies is welcome but not required. Strong English communication skills, independence, and teamwork in an interdisciplinary and international environment are important.
The position is supported by a newly funded interdisciplinary ETH research project. ETH Zurich offers access to state-of-the-art infrastructure, mentoring, training opportunities, and a collaborative research culture. Applications must be submitted online and should include a motivation letter, CV, academic records and degree certificates, a summary of research projects, and contact details for at least two academic referees. For scientific enquiries, contact Dr. Martin Béhé at [email protected]. More information about CRS is available at https://radiopharmaceutical-science.ethz.ch/ and https://www.psi.ch/en/crs.
Funding details
Available
What's required
Applicants should hold a Master's degree with an excellent academic record in Chemistry, Pharmaceutical Sciences, Biochemistry, Molecular Biology, Biotechnology, or a related discipline. Strong interest in radiopharmaceutical sciences, molecular imaging, protein engineering, glycobiology, or bioconjugation chemistry is expected. Practical experience in radiochemistry or radiopharmacy, cell biology and cell culture, protein or peptide chemistry, or preclinical in vivo research is an advantage. Excellent organizational and problem-solving skills are required, along with the ability to work independently and collaboratively in an interdisciplinary and international environment. Excellent written and oral communication skills in English are required. Prior experience in radiopharmaceutical research, PET/SPECT imaging, or animal studies is considered an advantage but is not required.
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.
Professors
Prof. at ETH Zürich
Switzerland
Research Interests
Pharmacology
Pharmaceutical Chemistry
Radiopharmaceutical Chemistry
Molecular Imaging
Preclinical Imaging
Prof. at ETH Zürich
Switzerland
Research Interests
Biochemistry
Pharmacology
Glycobiology
Chemical Biology
Protein Chemistry
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.