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Charles Lawrie

1 year ago

PhD Position: Nanoparticle Detection of Nucleic Acids from Pathogens University of Udine in Italy

Degree Level

PhD

Field of study

Oncology

Funding

Funded PhD Project (Students Worldwide)

Deadline

Expired

Country flag

Country

Italy

University

University of Udine

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Keywords

Oncology
Chemistry
Biomedical Engineering
Materials Science
Biotechnology
Biology
Health Science
Regulatory Compliance
Point-of-care Testing
Pathogen Detection
Commercialization
Nucleic Acid Chemistry
Biosensor
Clinical Application
Molecular Diagnostic

About this position

This PhD project focuses on developing and optimizing a novel nanoparticle-based biosensor platform for the rapid detection of nucleic acids from infectious pathogens. Traditional diagnostic methods such as PCR and sequencing, while accurate, are slow, expensive, and require centralized laboratory facilities, limiting their scalability for widespread diagnostic needs. The research aims to address these limitations by advancing a gold colloidal biosensor technology capable of direct detection of viral nucleic acids from biological fluids, eliminating the need for purification or amplification steps.

The project will expand the platform to detect multiple clinically relevant pathogens, validate its analytical and clinical performance, and prepare it for commercialisation and compliance with in vitro diagnostic regulations. Hosted at IIS Biogipuzkoa Health Research Centre in Spain, the work will be conducted within Dr. Charles Lawrie’s Molecular Oncology group, which integrates biomarker discovery, diagnostic tool development, and therapeutic innovation.

The laboratory offers access to advanced facilities for cell culture, flow cytometry, microscopy, genomics, histology, and clinical trials, as well as strong links to oncology medical services. The position is part of the INT2ACT Doctoral Network, providing opportunities for secondments at collaborating institutions, including Shanghai University in China. Candidates should have a Master’s degree in materials science, biomedical engineering, biotechnology, chemistry, or a related field, and must not already hold a doctoral degree. Desirable skills include bioinformatics, computational biology, nucleic acid detection, nanomaterials, biosensor development, and experience with medical device translation or regulatory aspects.

Strong motivation, multidisciplinary research interest, and proficiency in English are required. The position is fully funded under EU MSCA regulations, including salary, benefits, and travel support. Applications require a statement of interest, CV, academic certificates, and degree documentation, submitted as a single PDF. The deadline for applications is January 31, 2026.

Funding details

Funded PhD Project (Students Worldwide)

What's required

Applicants must hold a Master’s degree in a relevant discipline such as materials science, biomedical engineering, biotechnology, chemistry, or a related field. Candidates must not already possess a doctoral degree. Mobility rule applies: researchers must not have resided or carried out their main activity in Spain for more than 12 months in the 36 months immediately before recruitment. Experience in bioinformatics, computational biology, nucleic acid detection, nanomaterials, biosensor development, diagnostic assay validation, or regulatory aspects of medical devices is desirable. Strong interest in multidisciplinary research and good communication and teamwork skills are required. Proficiency in English is mandatory, demonstrated by a recognized test or relevant qualifications.

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Professors

Professor at INT2ACT

University Name
Country flag

Italy

Research Interests

Biology

Oncology

Health Science

Biomedical Engineering

Point-of-care Testing

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Biomedical Engineering

Oncology

Biology

Health Science

Clinical Application

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Cell Biology

Health Science

Biology

Biomedical Engineering

Bioinformatic

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Organic Chemistry

Biochemistry

Biology

Biotechnology

Health Science