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University Medical Center Utrecht
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PhD Student in Biophysics of Cellular Immunity University Medical Center Utrecht in Netherlands
Degree Level
PhD
Field of study
Computer Science
Funding
Paid PhD position with a gross monthly salary of €3,217–€4,077 based on full-time employment, plus an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities.
Deadline
Nov 23, 2026
Country
Netherlands
University
University Medical Center Utrecht
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About this position
This PhD project in the Vorselen Lab at University Medical Center Utrecht focuses on the biophysics of cellular immunity. The research explores how mechanical forces regulate immune function, with particular attention to how cells receive physical information and how cellular forces shape immune processes in health and disease.
You will work on developing new technologies and analysis approaches to study immune cell mechanics. A major part of the project is building new analysis pipelines to increase the throughput of cellular force measurements during phagocytosis and in therapeutic cytotoxic T cells. The work combines immune assays, high-resolution fluorescence imaging, and quantitative analysis to generate detailed readouts of immune cell behavior.
The project sits at the interface of biophysics and cellular immunology, using microscopy and molecular biology to study how physical forces influence immune responses. The aim is to generate new insights into the functional role of biophysical forces in immune cells and to advance tools that may help assess biophysical parameters as biomarkers.
You will be based in the laboratory of Dr. Daan Vorselen, within the computational immunology cluster of the Center for Translational Immunology. The group is described as small and diverse, and the center provides a well-facilitated research environment with expertise across immunology and access to state-of-the-art facilities such as flow cytometry and imaging.
Funding details
Paid PhD position with a gross monthly salary of €3,217–€4,077 based on full-time employment, plus an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities.
What's required
Applicants should hold a master’s degree or equivalent in biophysics, bionanoscience or bioinformatics (and biocomplexity), or a degree in life sciences with clear evidence of quantitative skills. The ideal candidate has experience with programming and image analysis, enthusiasm for developing new image analysis pipelines, and hands-on wet-lab experience including cell culture and fluorescent imaging. Strong motivation, meticulousness, proactivity, flexibility, responsibility, excellent communication and organizational skills, and the ability to work independently and in a team are required. Candidates should submit a motivation letter, CV, publication record if applicable, and details for at least two references.
How to apply
Send a motivation letter and CV, including past experience, publication record if applicable, and contact details for at least two references. Use the application link provided in the advert to apply. Questions can be directed by email to Daan Vorselen.
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Review drafts and confirm requirements with the university.
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.