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Gemma Langridge

11 months ago

PhD Studentship: Carrying a Toxic Burden – The Spread of Shiga Toxin stx2a-harbouring Phage in E. Coli University of East Anglia in United Kingdom

Degree Level

PhD

Field of study

Microbiology

Funding

Available

Deadline

Expired

Country flag

Country

United Kingdom

University

University of East Anglia

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Keywords

Microbiology
Biology
Health Science
Food Safety
Population Health
Bacteria
Bacterial Genetics
Clinical Data
Quantitative Pcr
Molecular Phylogeny
Genome-wide Association
Bacteriophage

About this position

[4-year fully-funded studentship including direct payment of tuition fees, annual stipend for living expenses (£20,780 for 2025/26), and a Research Training Support Grant each year.] This PhD studentship at the University of East Anglia investigates the ongoing spread of Shiga toxin stx2a-harbouring phage in E. coli, a major public health concern due to its association with severe foodborne illness and haemolytic uraemic syndrome (HUS). The project will explore the impact of multiple stx2a gene copies, prophage diversity, and additional genetic factors contributing to HUS. Research will integrate bacterial and phage genomics, clinical data analysis, qPCR expression assays, and laboratory assessment of prophage mobilisation. The aim is to inform public health surveillance and predict the emergence of novel pathogenic E. coli types.

The student will receive training from Dr Gemma Langridge (microbiology and E. coli genomics), Dr Evelien Adriaenssens (phage biology), and Dr Claire Jenkins (UK Health Security Agency lead for E. coli), gaining expertise in both laboratory and computational methods, including sequencing, qPCR, phage biology, phylogenomics, and genome-wide association studies. The programme includes a placement at the UK Health Security Agency, providing experience in translating research into practical public health methodologies. The student will be based at the Quadram Institute, a state-of-the-art facility on the Norwich Research Park, joining a vibrant community of microbiologists and informaticians. The studentship is fully funded for four years, covering tuition fees, a living stipend (£20,780 for 2025/26), and a Research Training Support Grant.

Applicants should have at least a UK equivalent Bachelors (Honours) 2:1 and meet English language requirements (IELTS 6.5 overall, 6 in each category). The programme starts on 1 October 2026. For application details, visit the UEA postgraduate research portal or contact Dr Gemma Langridge for informal enquiries.

Funding details

Available

What's required

Applicants must hold at least a UK equivalent Bachelors (Honours) degree with a minimum of 2:1 classification. English language proficiency is required, with an IELTS score of 6.5 overall and at least 6 in each category. The programme is full-time and starts on 1 October 2026.

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Professors

Dr. at University of East Anglia

University Name
Country flag

United Kingdom

Research Interests

Microbiology

Food Safety

Biology

Health Science

Bacterial Genetics

Dr. at University of East Anglia

University Name
Country flag

United Kingdom

Research Interests

Microbiology

Virology

Health Science

Bacteria

Biology

Dr. at University of East Anglia

University Name
Country flag

United Kingdom

Research Interests

Microbiology

Molecular Phylogeny

Genome-wide Association

Bacteriophage

Biology