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Linköping University

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Postdoc in Ion Channel Physiology, Electrophysiology and Pharmacology Linköping University in Sweden

Degree Level

Postdoc

Field of study

Molecular Biology

Funding

Full-time fixed-term employment for three years, funded by the Högbom-Cocozza Research Foundation, with a salary of SEK 43,000 per month. The postdoctoral researcher may spend 6–12 months at a higher education institution abroad with Foundation funding and may apply before the third year for an independent research grant of approximately SEK 500,000.

Deadline

Nov 30, 2026

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Country

Sweden

University

Linköping University

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Keywords

Molecular Biology
Biology
Electrophysiology
Neuropsychology
Medical Science
Pharmacy
Post-translational Modification
Channel Physiology

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About this position

Linköping University is seeking a postdoctoral researcher for a project on the endogenous regulation of ion channels and electrical excitability, and on how ion channel function is altered by disease and pharmaceutical compounds.

The research will examine posttranslational modifications of voltage-gated potassium ion channels involved in neuronal and cardiac excitability. The project will investigate how modifications such as channel phosphorylation influence channel function and pharmacology, and how these mechanisms can inform selective drug design. The researcher will study healthy wild-type channels as well as channels carrying disease-associated mutations.

Experimental work will primarily combine molecular biology with electrophysiological techniques in cellular systems, including Xenopus laevis oocytes and mammalian cells. The researcher will modulate signaling pathways and measure ion channel activity and responses to endogenous and exogenous regulation.

The postdoctoral researcher will join the Division of Cell- and Neurobiology within Linköping University’s Department of Biomedical and Clinical Sciences, working in Sara Liin’s research group. The group studies ion channels in cardiac, neuronal and smooth muscle tissue, with a focus on how endogenous molecules and genetic variants affect channel function and on developing compounds that rescue abnormal ion channel activity.

The research environment includes close collaboration with group members and researchers using complementary approaches such as molecular dynamics and structural biology, as well as interaction with local technical electrophysiology platforms. Research will be the principal activity, with teaching potentially comprising up to 20% of working hours.

Funding details

Full-time fixed-term employment for three years, funded by the Högbom-Cocozza Research Foundation, with a salary of SEK 43,000 per month. The postdoctoral researcher may spend 6–12 months at a higher education institution abroad with Foundation funding and may apply before the third year for an independent research grant of approximately SEK 500,000.

What's required

Applicants must hold a doctoral degree in medical sciences or a similar field, or an equivalent foreign doctoral degree, awarded no more than three years before the application deadline unless special grounds apply. The degree must be from a higher education institution other than Linköping University and must be awarded by the employment decision. Good theoretical and practical knowledge of electrophysiology in cellular systems is required, including hands-on experience studying ion channels in mammalian cells and/or Xenopus laevis oocytes. Extensive experience in ion channel physiology and pharmacology, especially voltage-gated ion channels, and experimental experience with posttranslational modifications are merits. Applicants should be structured, independent, committed to high quality, collaborative, and proficient in written and spoken English.

How to apply

Apply through the online “Apply” button and attach the required application documents, including selected research publications in PDF or Word format. Printed publications that cannot be submitted electronically should be mailed in three sets to the University Registrar at Linköping University.

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