Case Western Reserve University
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Postdoctoral Positions in In Situ Structural Biology and Cryo-ET at Case Western Reserve University Case Western Reserve University in United States
Degree Level
Postdoc
Field of study
Cell Biology
Funding
Postdoctoral position with sustained long-term NIH funding, competitive salary and benefits commensurate with NIH guidelines, and access to state-of-the-art cryo-EM/ET infrastructure and training.
Deadline
Sep 24, 2026
Country
United States
University
Case Western Reserve University

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About this position
Postdoctoral positions are open in the Zhu Laboratory at Case Western Reserve University, Cleveland, United States, in the area of in situ structural biology and cryo-electron tomography (cryo-ET).
The lab studies host-pathogen interactions, focusing on how host cells deploy antimicrobial defense machinery against invasive bacterial and parasitic pathogens. The research program uses advanced imaging and structural methods including cryo-ET, cryo-FIB/SEM, cryo-CLEM, and subtomogram averaging (STA) to determine high-resolution structures of host defense machineries and pathogen virulence factors in their native cellular environment.
Applicants should hold a PhD in structural biology, biophysics, microbiology, biochemistry, cell biology, or a related discipline. Prior cryo-EM/ET or cell biology experience is not required; the PI will provide systematic technical mentorship. The lab emphasizes mechanistic structural biology, scientific rigor, and training across cutting-edge structural and cell biology techniques.
The position is supported by long-term NIH funding and offers a supportive, collaborative environment with competitive salary and benefits. Applications are reviewed immediately and will continue until the positions are filled.
To apply, send a single PDF containing a cover letter describing your research background and career goals, a current CV, and contact information for two references to [email protected].
Funding details
Postdoctoral position with sustained long-term NIH funding, competitive salary and benefits commensurate with NIH guidelines, and access to state-of-the-art cryo-EM/ET infrastructure and training.
What's required
Applicants should have a PhD in structural biology, biophysics, microbiology, biochemistry, cell biology, or a related discipline. Prior experience in cryo-EM/ET or cell biology is not required, but enthusiasm for mechanistic structural biology and a strong commitment to scientific rigor are essential.
How to apply
Send a single PDF with a cover letter, CV, and contact information for two references to [email protected]. Applications are reviewed immediately until the positions are filled.
More information can be found here
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