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Case Western Reserve University

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Postdoctoral Positions in In Situ Structural Biology and Cryo-ET at Case Western Reserve University Case Western Reserve University in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Postdoctoral position with sustained long-term NIH funding, competitive salary and benefits commensurate with NIH guidelines, and access to state-of-the-art cryo-EM/ET infrastructure and training.

Deadline

Sep 24, 2026

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Country

United States

University

Case Western Reserve University

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Keywords

Cell Biology
Microbiology
Biophysics
Biology
Structural Biology
Innate Immunity
Cryo-electron Microscopy
Medical Science
Host-pathogen Interaction

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About this position

Postdoctoral positions are open in the Zhu Laboratory at Case Western Reserve University, Cleveland, United States, in the area of in situ structural biology and cryo-electron tomography (cryo-ET).

The lab studies host-pathogen interactions, focusing on how host cells deploy antimicrobial defense machinery against invasive bacterial and parasitic pathogens. The research program uses advanced imaging and structural methods including cryo-ET, cryo-FIB/SEM, cryo-CLEM, and subtomogram averaging (STA) to determine high-resolution structures of host defense machineries and pathogen virulence factors in their native cellular environment.

Applicants should hold a PhD in structural biology, biophysics, microbiology, biochemistry, cell biology, or a related discipline. Prior cryo-EM/ET or cell biology experience is not required; the PI will provide systematic technical mentorship. The lab emphasizes mechanistic structural biology, scientific rigor, and training across cutting-edge structural and cell biology techniques.

The position is supported by long-term NIH funding and offers a supportive, collaborative environment with competitive salary and benefits. Applications are reviewed immediately and will continue until the positions are filled.

To apply, send a single PDF containing a cover letter describing your research background and career goals, a current CV, and contact information for two references to [email protected].

Funding details

Postdoctoral position with sustained long-term NIH funding, competitive salary and benefits commensurate with NIH guidelines, and access to state-of-the-art cryo-EM/ET infrastructure and training.

What's required

Applicants should have a PhD in structural biology, biophysics, microbiology, biochemistry, cell biology, or a related discipline. Prior experience in cryo-EM/ET or cell biology is not required, but enthusiasm for mechanistic structural biology and a strong commitment to scientific rigor are essential.

How to apply

Send a single PDF with a cover letter, CV, and contact information for two references to [email protected]. Applications are reviewed immediately until the positions are filled.

More information can be found here

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