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Antonino Cassotta

9 months ago

Postdoctoral Positions in Tumor Immunology and Cellular Immunotherapy at Karolinska Institutet Karolinska Institutet in Sweden

Degree Level

Postdoc

Field of study

Molecular Biology

Funding

The position is a 2-year full-time temporary employment with possibilities for prolongation. Salary is paid monthly. The position is funded by a grant from the Swedish Research Council. Karolinska Institutet is a state university, offering benefits through a collective agreement. No specific stipend amount or tuition coverage is mentioned.

Deadline

Expired

Country flag

Country

Sweden

University

Karolinska Institutet

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Keywords

Molecular Biology
Immunotherapy
Biology
Medical Science
Cancer
Genome Editing
T Cell Biology
Tumor Immunology

About this position

Join the Center for Cellular Cancer Therapy (C3T) at Karolinska Institutet for a postdoctoral position in adaptive immunity and tumor immunology. The C3T is a leading research constellation funded by the Swedish Research Council, focusing on advancing cellular immunotherapies against cancer, especially solid tumors. The research environment is international, interdisciplinary, and collaborative, with access to state-of-the-art facilities in molecular biology, cell culture, animal models, flow cytometry, and imaging.

Two research groups are seeking postdoctoral researchers: Antonino Cassotta's team (antigen-specific human T cells, TCR sequencing, genome editing) and Yenan Bryceson's group (cytotoxic lymphocyte differentiation, transcriptional regulation). Projects include characterizing tumor-reactive T cells, TCR repertoire analysis, and developing new approaches for cellular therapy of advanced cancers. The work involves advanced molecular and cellular techniques, including cell culture, genetic manipulation, flow cytometry, (single-cell) RNA-seq, and animal experiments.

Applicants must have a PhD (or equivalent), strong scientific background, and hands-on experience in relevant methods. Required skills include first-author publication, human cell culture, cell sorting, molecular biology, and knowledge of immunology and cancer immunotherapy. Desirable skills include T cell engineering, TCR analysis, RNA sequencing, animal models, viral vectors, CRISPR/Cas9, and computational biology. Proficiency in English and excellent communication skills are essential.

The position is a 2-year full-time contract with possible extension, funded by the Swedish Research Council. Karolinska Institutet offers a creative, inspiring environment and benefits as a state university. Applications must be submitted via the Varbi system, including a cover letter, CV, publication list, and references. The deadline is March 2, 2026.

Funding details

The position is a 2-year full-time temporary employment with possibilities for prolongation. Salary is paid monthly. The position is funded by a grant from the Swedish Research Council. Karolinska Institutet is a state university, offering benefits through a collective agreement. No specific stipend amount or tuition coverage is mentioned.

What's required

Applicants must hold a PhD or a foreign degree equivalent to a Swedish PhD, completed preferably within the last three years. Required skills include at least one first-author publication in a peer-reviewed journal, hands-on experience with human cell culture, cell sorting, advanced flow cytometry, proficiency in molecular biology techniques (e.g., PCR, molecular cloning), good knowledge of immunology and cancer immunotherapy, and extensive experience with methods relevant to cellular immunotherapy. Excellent communication skills, motivation to work collaboratively, ability to work independently, and proficiency in spoken and written English are essential. Desirable skills include experience with culturing and engineering human primary T cells, TCR repertoire analysis, (single-cell) RNA sequencing, immunological methods (e.g., ELISA), animal models of cancer, viral vectors for cell transduction, CRISPR/Cas9 genome editing, knowledge in R, statistics, Linux, and programming languages such as Java.

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Professors

Assistant Professor

University Name
Country flag

Sweden

Research Interests

Immunology

T Cell Biology

Regulatory T Cells

Autoimmunity

Immunomodulation