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Philipps-Universität Marburg
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Postdoctoral Research Assistant in GPCR Optical Biosensors and Developmental Cell Biology Philipps-Universität Marburg in Germany
Degree Level
Postdoc
Field of study
Cell Biology
Funding
Full-time, three-year position with salary and benefits according to the Hesse public service collective agreement, TV-H pay grade E 13. The position includes equal pay under the Hesse Collective Agreement and a ticket for free use of public transport throughout Hesse, Germany. Career development training and professional development opportunities, including training, coaching, and mentoring, are offered.
Deadline
Nov 22, 2026
Country
Germany
University
Philipps-Universität Marburg
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About this position
Philipps-Universität Marburg is seeking a postdoctoral research assistant for the Department of Biology research group Developmental Genetics and Cell Biology of Animals, led by Professor Christian Helker.
The project focuses on the design, cloning, and application of optical biosensors for investigating the conformational dynamics of G protein-coupled receptors (GPCRs). The researcher will develop new biosensor fusion proteins and validate their performance in living cells, creating tools to measure receptor behavior in real time.
The work will examine how GPCRs respond to ligand binding and mechanical signals. It combines molecular biology, cell biology, pharmacology, and quantitative data analysis. The researcher will design and perform pharmacological and cell-biological assays in microtiter-plate formats, including assays with at least 96 wells, and will analyze and visualize large pharmacological datasets.
An additional component involves structural modeling of GPCR–ligand interactions, providing an opportunity to connect experimental biosensor development with molecular-level interpretation of receptor signaling. The position is embedded in a collaborative, innovative, and supportive research environment within a broad biology department.
The role offers opportunities for independent scientific work and further qualification as a postdoctoral researcher, supported by career development training, coaching, and mentoring.
Funding details
Full-time, three-year position with salary and benefits according to the Hesse public service collective agreement, TV-H pay grade E 13. The position includes equal pay under the Hesse Collective Agreement and a ticket for free use of public transport throughout Hesse, Germany. Career development training and professional development opportunities, including training, coaching, and mentoring, are offered.
What's required
Applicants must have an MSc degree or equivalent and a PhD in the life sciences, or provide evidence that doctoral studies are nearing completion. Extensive experience with molecular biology techniques for cloning new fusion proteins and with pharmacological assays in living cells using microtiter plates of at least 96 wells is required. Previous research experience involving GPCRs, G proteins, GRKs, or arrestins is required. Experience designing and validating new biosensors for use in living cells is desirable. Very good English skills are required.
How to apply
Apply online through the University of Marburg application button by 22 November 2026. Submit the required application materials through the online application portal.
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Prepare your application
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