King's College London
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Postdoctoral Research Associate in DNA Replication Timing and Chromosomal Translocations at King's College London King's College London in United Kingdom
Degree Level
Postdoc
Field of study
Immunology
Funding
This is a full-time, fixed-term postdoctoral position funded by Cancer Research UK (CRUK). The contract runs until 31/01/2030 with possible extension. Salary details are not stated in the post.
Deadline
Sep 30, 2026
Country
United Kingdom
University
King's College London
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About this position
King’s College London is recruiting two postdoctoral researchers for the Pavri Group, led by Dr. Rushad Pavri, in the School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine.
The project focuses on DNA replication timing, chromosomal translocations, B cells, immunology, cancer biology, and genomics. The lab studies how somatic hypermutation and DNA double-strand breaks contribute to genome instability and tumorigenic rearrangements, with a particular interest in mechanisms that drive translocation biogenesis at proto-oncogenes and immunoglobulin loci.
This CRUK-funded postdoctoral project combines CRISPR engineering of B cells, protein biochemistry, replication timing measurements, replication origin mapping, translocation-capture sequencing, and 3D genome architecture analyses. Candidates will work on identifying factors that establish early replication timing, understanding how these factors promote translocation formation, and testing mechanisms in preclinical models.
Applicants should have a PhD in a relevant biomedical science field, or be near completion. Strong publication record, molecular biology and genomics experience, biochemistry knowledge, critical thinking, independence, and teamwork are emphasized. Experience in B cells, immunology, cancer biology, gene regulation, DNA replication, next-generation sequencing, or bioinformatics is desirable but not essential.
The position is full-time (35 hours/week) and fixed term until 31 January 2030, with possible extension. The deadline is 30 September 2026. Interviews are expected on 2–4 November 2026.
Apply via the King’s College London jobs portal and submit a CV plus supporting statement addressing the essential criteria.
Funding details
This is a full-time, fixed-term postdoctoral position funded by Cancer Research UK (CRUK). The contract runs until 31/01/2030 with possible extension. Salary details are not stated in the post.
What's required
Applicants should hold a PhD in a relevant biomedical science discipline, or be very close to completing one within the next few months. Essential requirements include a strong publication record with first-author peer-reviewed publication(s) (preprints considered), a strong background in molecular biology and genomics, knowledge of biochemistry methods, critical thinking, ability to independently design and conduct experiments, professional written and oral communication, and teamwork. Experience with B cells, immunology, cancer biology, gene regulation, DNA replication, genomics, next-generation sequencing, or basic bioinformatics is desirable.
How to apply
Apply through the King’s College London jobs portal using the View or Apply link. Submit a CV and a supporting statement showing how you meet the essential criteria; include evidence for desirable criteria if possible.
More information can be found here
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