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St. Jude Children's Research Hospital

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Postdoctoral Research Associate in Pharmacogenomics, Functional Genomics, and Precision Pediatric Cancer Medicine St. Jude Children's Research Hospital in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Full-time permanent postdoctoral position with competitive compensation starting at $72,500 per year, comprehensive benefits, and generous relocation assistance. The position also provides access to shared research facilities, professional-development programs, a professional-development allowance, and career-growth resources.

Deadline

Dec 29, 2026

Country flag

Country

United States

University

St. Jude Children's Research Hospital

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Keywords

Cell Biology
Chemistry
Immunotherapy
Cancer Biology
Biology
Precision Medicine
Functional Genomics
Chemical Biology
Medical Science
Genome Editing
Pharmacy
Pediatric Oncology
Drug Response
Pharmacogenomic

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About this position

St. Jude Children's Research Hospital in Memphis, Tennessee, United States, is seeking a Postdoctoral Research Associate for the Yang Laboratory in the Department of Pharmacy and Pharmaceutical Sciences and the Center for Pharmacogenomics.

The project investigates the genetic and molecular basis of variability in treatment response in childhood cancer. Research integrates pharmacogenomics, multi-omics and computational analyses, experimental functional genomics, and precision medicine, with emphasis on targeted agents and immunotherapeutics.

Current research directions include genetic and multi-omic mechanisms of anticancer drug efficacy and treatment-related toxicity; single-cell studies of targeted-therapy response and immunotherapy resistance in childhood leukemia; large-scale gene-drug interaction studies using functional genomics; and chemical biology approaches involving molecular glues and proteolysis-targeting chimeras for high-risk leukemias.

The successful candidate will be an experienced bench scientist with expertise in experimental biology and/or molecular pharmacology, lead an independent subproject, collaborate with clinicians, statistical geneticists, and computational biologists, publish peer-reviewed research, and pursue external postdoctoral fellowship and funding opportunities.

Applicants need a PhD or equivalent in pharmacology, pharmaceutical sciences, genetics, molecular biology, or a related biomedical field. PharmD or MD candidates with substantial research experience may also be considered. A publication record and experience in pharmacology, human genetics, functional genomics, genome editing, or animal models are required. CRISPR screening, drug-sensitivity profiling, cancer biology, cancer therapy, or treatment-related toxicity experience is preferred.

The position is full time and offers a starting salary of $72,500 per year, comprehensive benefits, generous relocation assistance, research resources, and professional-development support. The application deadline is December 29, 2026.

Funding details

Full-time permanent postdoctoral position with competitive compensation starting at $72,500 per year, comprehensive benefits, and generous relocation assistance. The position also provides access to shared research facilities, professional-development programs, a professional-development allowance, and career-growth resources.

What's required

Applicants must hold a PhD or equivalent doctoral degree in pharmacology, pharmaceutical sciences, genetics, molecular biology, or a related biomedical field before the start date; candidates with a PharmD or MD and substantial research experience may also be considered. Applicants should have a strong record of research productivity demonstrated by peer-reviewed publications, knowledge and experience in at least one of pharmacology, human genetics, functional genomics, genome editing, or animal models, and strong written and oral English communication skills. The ability to work independently and collaboratively in a multidisciplinary environment is required. Preferred qualifications include experience with large-scale functional genomics, in vitro or in vivo CRISPR screening, high-throughput drug-sensitivity profiling, preclinical drug evaluation, cancer biology, cancer therapy, or treatment-related toxicity.

How to apply

Apply through the St. Jude careers portal. Submit a cover letter describing research interests, technical background, career goals, and availability; a CV with a complete publication list; a one- to two-page research experience and interests statement; and contact information for three professional references.

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