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Dana-Farber Cancer Institute

Postdoctoral Research Fellow in Biochemistry and Structural Biology of Transcriptional Control Dana-Farber Cancer Institute in United States

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Full-time permanent postdoctoral position with a stated salary range of $72,000 to $76,385.

Deadline

Jan 5, 2027

Country flag

Country

United States

University

Dana-Farber Cancer Institute

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Keywords

Biochemistry
Molecular Biology
Chemistry
Biology
Crystallography
Structural Biology
Functional Genomics
Cancer Research
Cryo-electron Microscopy
Chemical Biology
Medical Science
Transcriptional Regulation

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About this position

The Wachter Lab at Dana-Farber Cancer Institute in Boston, Massachusetts, is seeking a postdoctoral research fellow to investigate fundamental questions in the molecular mechanisms of transcriptional control.

The lab is a structural and chemical biology group studying transcriptional regulation associated with human diseases, including cancer. Its research integrates molecular biology, structural biology, functional genomics, proteomics, and computationally guided approaches to understand how molecular machines operate and to identify insights relevant to therapeutic development.

The fellow will work on biochemistry and structural biology projects involving mechanisms of transcriptional control. The research environment provides access to advanced facilities and expertise in cryo-electron microscopy, X-ray crystallography, nuclear magnetic resonance, chemistry, biophysics, cellular imaging, and in-house cryo-EM screening through the Dana-Farber Chemical Biology Program.

The position is based at the Dana-Farber Cancer Institute's Longwood Center, with an affiliation to the pediatrics department at Harvard Medical School. The successful researcher will join a highly interactive and collaborative team working at the interface of structural biology, molecular biology, and cancer research.

Funding details

Full-time permanent postdoctoral position with a stated salary range of $72,000 to $76,385.

What's required

Applicants should have a recent Ph.D. or equivalent degree in structural biology, biochemistry, biophysics, or molecular biology. Candidates must demonstrate the ability to develop and execute complex structural biology projects, collect and analyze experimental data, prepare research publications, communicate results, and work collaboratively. Expertise in at least two of the following areas is expected: recombinant protein expression and purification; insect or mammalian expression systems; X-ray or cryo-EM data collection and structure determination; protein biophysical techniques; in vitro biochemistry and enzyme kinetics; and quantitative or computational methods. Excellent oral and written communication skills are required.

How to apply

Apply through the external Nature Careers listing using the provided application link. Review the posting and submit the requested application materials through the employer's application process.

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