Publisher
source

Sergi Padilla-Parra

Just Landed

New Today

Postdoctoral Research Opportunity in AI-Based Red Fluorescent Proteins for Deep-Tissue Neuroimaging Instituto Biofisika in Spain

Degree Level

Postdoc

Field of study

Computer Science

Funding

Available

Deadline

Dec 2, 2026

Country flag

Country

Spain

University

Instituto Biofisika

Apply for this position

Keywords

Computer Science
Molecular Biology
Chemistry
Biomedical Engineering
Biophysics
Biology
Neuroimaging
Structural Biology
Artificial Intelligence
Photophysics
Neuropsychology
Protein Engineering
Physics

Suggested positions

Publisher
source

Weill Cornell Medicine

Country flag

United States

Weill Cornell Medicine is advertising a Postdoctoral Associate in Biochemistry & Biophysics in the Reck-Peterson Lab , focused on the mechanisms of intracellular transport across molecular, cellular, and organismal scales. The project areas include: (1) how defects in intracellular transport contribute to neurodegenerative disease , with emphasis on LRRK2 and Parkinson’s disease ; (2) mechanisms of organelle “hitchhiking” in filamentous fungi and their implications for secondary metabolite produ...

Cell Biology
Biochemistry
Molecular Biology
+8 more

1 month ago

Publisher
source

University of Bath

Country flag

United Kingdom

PhD opportunity at the University of Bath in the Faculty of Science , starting September 2027 . This interdisciplinary project sits at the interface of artificial intelligence , protein engineering , enzymology , and structural biology . The research will investigate why closely related enzymes in the same family act either as peptidases (peptide-cutting proteases) or ligases (peptide-joining enzymes). The project combines AI-driven protein analysis , directed enzyme evolution , biochemical char...

Computer Science
Chemistry
Biomedical Engineering
+6 more

1 week ago

Publisher
source

Centre for Genomic Regulation

Country flag

Spain

PhD opportunity at the Centre for Genomic Regulation (CRG), Barcelona, Spain. This funded PhD project is part of the CRG International PhD Programme 2027 and focuses on decoding the molecular rules by which sensor proteins can monitor highly diverse and specific environmental chemicals . The project combines large-scale mutagenesis and functional data generation , AI-enhanced evolutionary modeling , and engineering of chemically inducible protein folds . It is a strong fit for candidates interes...

Computer Science
Molecular Biology
Chemistry
+7 more

1 month ago

Publisher
source

Bo Liang

Emory University

Country flag

United States

Emory University School of Medicine’s Liang Laboratory in Atlanta, United States, is recruiting three full-time Postdoctoral Fellows: two positions in Cryo-Electron Microscopy (Cryo-EM) and Structural Biology, and one in Cryo-Electron Tomography (Cryo-ET) and In Situ Structural Biology. The laboratory combines structural biology, protein biochemistry, biophysics, and computational methods to study viral RNA synthesis machinery, viral replication, disease-associated amyloid filaments, and protein...

Computer Science
Chemistry
Biomedical Engineering
+10 more

Posted Yesterday

Publisher
source

Daniel Keedy

CUNY Advanced Science Research Center

Country flag

United States

The Keedy Lab at the CUNY Advanced Science Research Center in New York City is advertising a postdoctoral position in computational and experimental structural biology . The lab uses a “statistical structural biology” approach, combining high-throughput crystallography with computational analyses to study how protein dynamics relate to protein function . The goal is to move beyond static structural snapshots and uncover the conformational ensembles that underlie biological activity. This opportu...

Computer Science
Chemistry
Biomedical Engineering
+7 more

3 weeks ago

About this position

The Padilla-Parra Laboratory at Instituto Biofisika is offering a postdoctoral research opportunity at the intersection of artificial intelligence, protein engineering, and advanced neuroimaging. The project focuses on designing next-generation red and far-red fluorescent proteins for deep-tissue imaging, with a particular emphasis on the mammalian brain.

The successful researcher will work on computationally designing novel fluorescent protein variants using modern protein language models and related AI tools, then move these candidates into experimental testing. The work spans sequence design, cloning and expression in bacterial and mammalian systems, purification, biophysical and structural characterisation, and evaluation in neuronal and brain tissue imaging settings.

This is a highly interdisciplinary position that brings together expertise in quantitative fluorescence microscopy, protein biophysics, neuroscience, and computational molecular design. The project is based in the Padilla-Parra Laboratory at Instituto Biofisika, an internationally active research group known for work in fluorescence microscopy and optical tools for biology. It also includes close collaboration with researchers at CIC biomaGUNE, the Achucarro Basque Center for Neuroscience, and Onava, creating a network that links academic and industrial expertise.

The postdoctoral researcher will contribute to advanced imaging studies using two- and three-photon microscopy, protein photophysics, and quantitative image analysis. The role also includes participation in collaborative research activities, scientific publications, grant preparation, conference presentations, and co-supervision of PhD and Master's students within the laboratory.

Instituto Biofisika provides access to strong interdisciplinary infrastructure and a collaborative environment spanning biophysics, structural biology, advanced imaging, and high-performance computing.

Funding details

Available

What's required

Applicants must have a PhD in Physics, Chemistry, Biochemistry, Biology or a closely related discipline awarded before the contract start date. A strong background in molecular biology techniques is required, including cloning, site-directed mutagenesis, recombinant protein expression and purification. Experience in biophysical characterisation methods such as spectroscopy, fluorescence lifetime imaging or equivalent techniques is required, along with proficiency in fluorescence microscopy and/or deep-tissue imaging. Applicants should have a demonstrated publication record in peer-reviewed international scientific journals, excellent written and spoken English, and the ability to work independently, manage a research project, and contribute constructively to a multidisciplinary team. Desirable experience includes AI-based or computational protein design tools, two-photon or three-photon microscopy, advanced image analysis, primary neuronal cell cultures or ex vivo brain tissue preparation, Python or equivalent programming tools, and previous fluorescent protein engineering or photophysics experience.

How to apply

Email a single PDF application containing a cover letter, full CV with publications, and contact details for two or three academic referees. Send it to Prof. Sergi Padilla-Parra at [email protected] with the specified job application subject line. Apply as early as possible because applications are reviewed on a rolling basis until the position is filled.

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts and confirm requirements with the university.

Professors

Prof. at Instituto Biofisika

University Name
Country flag

Spain

Research Interests

Neuropsychology

Artificial Intelligence

Neuroimaging

Biomedical Engineering

Photophysics