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Kirsty Spalding

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Postdoctoral Researcher in Adipocyte Cell Cycle Reactivation and Senescence Karolinska Institutet in Sweden

Degree Level

Postdoc

Field of study

Metabolism

Funding

Postdoctoral researcher position at Karolinska Institutet; temporary full-time employment. The lab is supported by the Knut and Alice Wallenberg Foundation, the Swedish Research Council and the Novo Nordisk Foundation, but no stipend or salary amount is stated.

Deadline

Sep 9, 2026

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Country

Sweden

University

Karolinska Institutet

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Keywords

Metabolism
Medical Imaging
Biology
Computational Biology
Adipose Tissue Biology
Aging
Cell Signaling
Medical Science
Dna Damage
Statistics

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About this position

Postdoctoral Researcher in Adipocyte Cell Cycle Reactivation and Senescence at Karolinska Institutet (Solna, Sweden).

This postdoctoral project sits in the Spalding research group at the Department of Cell and Molecular Biology (CMB), with a strong focus on human adipose tissue biology, cell signalling, cell cycle biology, senescence, metabolism, and DNA replication/remodelling. The project investigates how mature human adipocytes re-enter the cell cycle under chronic hyperinsulinaemia, why the response differs between adipose depots, and how this maladaptive process may be redirected to reduce senescence and inflammation.

The successful candidate will work with human adipose tissue biopsies and primary human adipocytes, combining cell and molecular biology, imaging-based methods, and computational approaches. The lab has access to imaging, flow cytometry, single-cell and bulk omics, and proteomics platforms, and benefits from strong clinical collaborations in Sweden and internationally.

Eligibility and profile: a PhD (or equivalent) is required by the employment decision date. Strong experience in cell signalling and/or cell cycle biology, immunocytochemistry/immunohistochemistry, time-lapse and confocal microscopy, and computational/statistical analysis is expected. Background in adipose tissue biology, metabolism, senescence, or DNA damage/replication biology is a strong advantage. Good English and the ability to work independently in a collaborative setting are important.

Funding and employment: this is a temporary full-time postdoctoral employment at Karolinska Institutet. No stipend amount is given; the position is salaried under KI collective agreements.

Application deadline: 2026-09-09. Apply via the Varbi recruitment system and include the requested documents in English or Swedish.

Funding details

Postdoctoral researcher position at Karolinska Institutet; temporary full-time employment. The lab is supported by the Knut and Alice Wallenberg Foundation, the Swedish Research Council and the Novo Nordisk Foundation, but no stipend or salary amount is stated.

What's required

A PhD or foreign degree deemed equivalent to a Swedish PhD is required by the time of employment decision. Completion of the doctorate within the last three years is considered an advantage. Required and desirable experience includes expertise in cell signalling and/or cell cycle biology, including protein-protein interactions; immunocytochemistry/immunohistochemistry; time-lapse and confocal microscopy; strong computational and statistical expertise; background in adipose tissue biology, metabolism, senescence or DNA damage/replication biology; primary mammalian cell culture, with human adipose tissue experience an advantage. Applicants must be able to work independently, contribute collaboratively, and have good written and spoken English.

How to apply

Prepare the required documents in English or Swedish: PhD certificate, complete CV with thesis and academic details, complete publication list, and a one-page summary of current work. Submit the application through the Varbi recruitment system before the deadline.

More information can be found here

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