Vincent Pasque
Top university
6 days ago
Postdoctoral Researcher in Stem Cell Biology and Early Human Development KU Leuven in Belgium
Degree Level
Postdoc
Field of study
Computer Science
Funding
Available
Deadline
Sep 30, 2026
Country
Belgium
University
KU Leuven

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About this position
The Pasque lab at KU Leuven is recruiting a postdoctoral researcher to investigate stem cell biology and early human development. The project focuses on how pluripotency, epigenetic regulation, cell fate decisions, and gene regulatory networks shape peri-implantation and postimplantation development, with particular interest in extraembryonic lineages and X-chromosome inactivation.
The work is embedded in the Faculty of Medicine, Department of Development and Regeneration, within the stem cell and development cluster and affiliated with the Leuven Single-Cell Omics Institute. The project is highly collaborative and is carried out with Dr. Claire Rougeulle (Curie Institute, France), Dr. Laurent David (University of Nantes, France), Dr. Thierry Voet (KU Leuven), and other researchers in the field.
The successful candidate will develop and apply stem cell-based embryo models, including blastoids, and use CRISPR perturbations, microscopy, and single-cell multi-omics approaches to study early human embryo development. The role combines wet-lab experimentation with data generation and analysis, and may include engagement with computational biology and interdisciplinary collaboration.
Applicants must hold a PhD in a relevant life science area such as stem cell biology, developmental biology, or molecular biology. A strong publication record is expected, along with experience in mammalian stem cells, gene regulation, and molecular methods. Experience with cell culture, transcriptomics, epigenomics, early embryogenesis, human pluripotent stem cells, embryo models, microscopy, RNA FISH, single-cell genomics, and computational biology is considered advantageous.
The position offers a competitive salary under KU Leuven standards, an initial one-year appointment, and the possibility of extension up to three years depending on performance and funding availability. The lab offers access to state-of-the-art facilities, a dynamic international research environment, and opportunities for scientific and professional development. The post is based in Leuven, Belgium, with an application deadline of 2026-09-30.
Funding details
Available
What's required
A PhD in Life Sciences, Stem Cell Biology, Developmental Biology, Molecular Biology, or a related discipline is required. Applicants should have a strong publication record in peer-reviewed international journals and demonstrated expertise in mammalian stem cells, gene regulation, and molecular techniques. Prior experience in cell culture, molecular biology, transcriptomics, epigenomics, early mammalian embryogenesis, human pluripotent stem cells, epigenetics, X-chromosome inactivation, embryo models, microscopy, RNA FISH, single-cell genomics, and computational biology is an advantage. Strong enthusiasm for collaborative interdisciplinary research in early human development is expected.
How to apply
Submit a cover letter describing your research interests and technical expertise, a detailed CV including a full publication list, and contact information for 3 professional referees. Direct questions about the vacancy to prof. Vincent Pasque at [email protected].
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