Aaron Goldman

Assistant Professor

The Wistar Institute

United States

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About

Dr. Aaron Goldman is an Assistant Professor at The Wistar Institute in the United States. His research focuses on a range of topics including therapeutic vulnerabilities in ARID1A-mutant ovarian cancer, HIV-1 latency mechanisms, and the metabolic implications of cancer treatments. Dr. Goldman's recent articles explore significant immune factors influencing HIV pathogenesis, metabolic reprogramming in cellular senescence, and the connections between intestinal microbiota and biological aging.

Articles (20)

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2025

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2021

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2021

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2020

Collaborators (17)

Janusz Franco-Barraza

Assistant Research Professor

Fox Chase Cancer Center

UNITED STATES

Aaron Goldman

Research Interests

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Articles (20)

Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer.

Ex vivo and in vivo HIV-1 latency reversal by "Mukungulu," a protein kinase C-activating African medicinal plant extract.

Selective abrogation of S6K2 identifies lipid homeostasis as a survival vulnerability in MAPK inhibitor-resistant NRAS-mutant melanoma.

METTL3-mediated chromatin contacts promote stress granule phase separation through metabolic reprogramming during senescence.

Host genetic and immune factors drive evasion of HIV-1 pathogenesis in viremic non-progressors.

Prepandemic Metabolic Correlates of Coronavirus Disease 2019 (COVID-19) Severity and Long COVID Incidence in People Living With HIV.

Circulating immune and plasma biomarkers of time to HIV rebound in HIV controllers treated with vesatolimod.

4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.

Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death.

Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging.

Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer

Lysosomal lipid peroxidation regulates tumor immunity

Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression

Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV

Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine–Thiol Displacement Reaction

A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism

Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer.

Collaborators (17)

Janusz Franco-Barraza

seokwoo lee

Rugang Zhang

Patricia Resa-Infante

Ralph Francescone

michela perego

Monika Bhardwaj

Maria Salgado

Valentina Vaira

Toshitha Kannan

Qiang Zhang

Lucia Languino

Rongsheng E. Wang

Stephan Kemp

Leila Giron

Andrew E. Aplin

Lidia Garrido-Sanz

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