Adam Linley
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Senior Lecturer in Haematology
United KingdomResearch Interests
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About
Adam Linley is a Senior Lecturer in Haematology at Liverpool John Moores University in the UK. His research primarily focuses on the mechanisms of calcium signaling in malignant B-cells, resistance mechanisms to Bruton's Tyrosine Kinase inhibitors, and the reprogramming of BCR signaling in chronic lymphocytic leukemia (CLL). His recent publications highlight the significance of ZAP70 in determining prognosis within CLL patients.
Recent Grants
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Kinomic reprogramming during clonal evolution and therapy resistance in chronic lymphocytic leukaemia.
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Kinome profiling and mass cytometry as tools to detect rewiring of B cell receptor signalling in the malignant cells of chronic lymphocytic leukaemia patients taking ibrutinib.
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Interrogation of the B-cell receptor response in CLL using ALACAT proteomics to define tumour signalling responses to therapy and resistance
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Articles (4)
Year:
2022
Year:
2022
Year:
2021
Year:
2021
Collaborators (4)
Francesco Forconi
University of Southampton
Skye Montoya
Yale University
Eric Wang
Assistant Professor
Jackson Laboratory - Farmington
Joseph Slupsky
Professor
University of Liverpool
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