Adjia Hamadjida

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Canada

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Adjia Hamadjida is an Associate Professor in the Department of Neurosciences at Université de Montréal, Canada. Her research focuses on neuropharmacology, including the effects of mGlu2 receptor modulators on dyskinesias in Parkinson's models, as well as investigating neuroprotective properties of various plant extracts. Recent publications highlight her work on the neuroprotective and antioxidant activities of Hibiscus sabdariffa and the pharmacokinetics of different pharmacological compounds in preclinical models.

Recent Grants

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Resaerch grant

Open Date: 2023-01-01

Close Date: 2025-12-01

Grant: Close

Ibro return home

Open Date: 2022-01-01

Close Date: 2024-01-01

Articles (15)

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2025

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2025

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2022

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2021

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2020

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2020

Collaborators (4)

Daniel Lévesque

Professor

Université de Montréal

CANADA

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Francis Beaudry

Professor / professeur titulaire

Université de Montréal

CANADA

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Claude Rouillard

Professeur

Laval University

CANADA

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Paul Clarke

Professor

McGill University

CANADA

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Adjia Hamadjida

Research Interests

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Recent Grants

Articles (15)

Effect of the mGlu2 receptor positive allosteric modulator AZD8529 on L-DOPA-induced dyskinesia and psychosis-like behaviours in the parkinsonian marmoset

Mostuea batesii Baker (Gelsemiaceae) root bark hydroethanolic extract unveil neuroprotective, antihypertensive, and antioxidant activities in rat model exposed to lead acetate

The anti-dyskinetic effect of the clinic-ready mGluR2 positive allosteric modulator AZD8529 in the 6-OHDA-lesioned rat

Hibiscus sabdariffa Linn. protects against cerebral ischemia-reperfusion injury via regulation of oxidative stress markers and inflammation

Effect of the mGlu2 positive allosteric modulator biphenyl‐indanone A as a monotherapy and as adjunct to a low dose of L‐DOPA in the MPTP‐lesioned marmoset

Neuroprotective effects of Hibiscus sabdariffa var. altissima on cerebral ischemia‒Reperfusion injury in rats

Antioxidant and anti-inflammatory effects of Boswellia dalzielii and Hibiscus sabdariffa extracts in alloxan-induced diabetic rats

The 5‐HT2A/2C inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset

Pharmacokinetic profile of bitopertin, a selective GlyT1 inhibitor, in the rat

Autoradiographic labelling of 5-HT3 receptors in the hemi-parkinsonian rat brain

Anti-parkinsonian effect of the mGlu<sub>2</sub> positive allosteric modulator LY-487,379 as monotherapy and adjunct to a low L-DOPA dose in the MPTP-lesioned marmoset.

Effect of glycine transporter 1 inhibition with bitopertin on parkinsonism and L-DOPA induced dyskinesia in the 6-OHDA-lesioned rat.

Co-registration of Imaging Modalities (MRI, CT and PET) to Perform Frameless Stereotaxic Robotic Injections in the Common Marmoset.

The highly selective mGlu<inf>2</inf> receptor positive allosteric modulator LY-487,379 alleviates l-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease

Selective metabotropic glutamate receptor 2 positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.

Collaborators (4)

Daniel Lévesque

Francis Beaudry

Claude Rouillard

Paul Clarke

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