Adolfo Garcia-Sastre

Professor

Icahn School of Medicine at Mount Sinai

United States

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About

Adolfo Garcia-Sastre is a Professor at the Icahn School of Medicine at Mount Sinai in the United States. His research primarily focuses on viral pathogenesis, including influenza and coronaviruses, as well as their interactions with host cells. Recent publications highlight his work on the regulatory mechanisms of SARS-CoV-2, the emergence of avian influenza in livestock, and innovative approaches for cancer therapy using RNA viruses.

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2022

Collaborators (26)

David Gerber

Professor of Internal Medicine (Hematology-Oncology) and Clinical Sciences

University of Texas Southwestern Medical Center

UNITED STATES

Adolfo Garcia-Sastre

Research Interests

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Articles (20)

Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.

Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation

Pandemic risk stemming from the bovine H5N1 outbreak: an account of the knowns and unknowns

Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer

Visualization of Early RNA Replication Kinetics of SARS-CoV-2 by Using Single Molecule RNA-FISH Combined with Immunofluorescence

Recombination across distant coronavirid species and genera is a rare event with distinct genomic features

Comparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV

Avian influenza A (H5N1) virus in dairy cattle: origin, evolution, and cross-species transmission

ACE2 and TMPRSS2 distribution in the respiratory tract of different animal species and its correlation with SARS-CoV-2 tissue tropism

Generation of a high yield vaccine backbone for influenza B virus in embryonated chicken eggs

SARS-CoV-2 Neutralizing Antibodies in Free-Ranging Fallow Deer (Dama dama) and Red Deer (Cervus elaphus) in Suburban and Rural Areas in Spain

Multicomponent intranasal adjuvant for mucosal and durable systemic SARS-CoV-2 immunity in young and aged mice

A Small Molecule RIG-I Agonist Serves as an Adjuvant to Induce Broad Multifaceted Influenza Virus Vaccine Immunity

Antigenic Landscape Analysis of Individuals Vaccinated with a Universal Influenza Virus Vaccine Candidate Reveals Induction of Cross-Subtype Immunity

Engineering Non-Human RNA Viruses for Cancer Therapy

Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza.

SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules

Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine

Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison

Human SUMOylation Pathway Is Critical for Influenza B Virus

Collaborators (26)

David Gerber

Benjamin Hale

Briana Lynn McGovern

Estanislao Nistal-Villán

Ganjam Kalpana

Luis Martinez-Sobrido

Gustavo Palacios

Jennifer King

Silke Stertz

Vicente Marchán

Sara Cuadrado-Castano

MARIA T SANCHEZ-APARICIO

Juan Ayllon Barasoain

Jorge Gomez

Udeni B. R. Balasuriya

Michael Schotsaert

Kris White

Chih-Yuan Hsu

Teresa Allende Aydillo Gomez

José Gallego

Harm van Bakel

Andrew Bowman

Alberto E. Paniz-Mondolfi

Juan Manuel Carreno Quiroz

Mahmoud Naguib

Randy Albrecht

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