Adrian Rothenfluh

Associate Professor

University of Utah

United States

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Adrian Rothenfluh is an Associate Professor at the University of Utah, USA. His research focuses on the neurobiological mechanisms of addiction and sleep deficits, utilizing invertebrate models such as Drosophila . Recent publications include investigations into synaptic mechanisms of ethanol tolerance, the role of neuronal E93 in metabolism, and innovative methodologies leveraging ATAC-seq for studying neuronal subtypes.

Articles (14)

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2025

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2020

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2020

Collaborators (1)

Shin Yamazaki

Professor

Southwestern Medical Center

UNITED STATES

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Adrian Rothenfluh

Research Interests

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Articles (14)

Alcohol induces long-lasting sleep deficits in Drosophila via subsets of cholinergic neurons.

Synaptic Mechanisms of Ethanol Tolerance and Neuroplasticity: Insights from Invertebrate Models

Neuronal E93 is required for adaptation to adult metabolism and behavior.

Iterative assay for transposase-accessible chromatin by sequencing to isolate functionally relevant neuronal subtypes.

Large analysis of genetic manipulations reveals an inverse correlation between initial alcohol resistance and rapid tolerance phenotypes.

The Stage-Based Model of Addiction—Using <i>Drosophila</i> to Investigate Alcohol and Psychostimulant Responses

Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs.

Optimized assay for transposase-accessible chromatin by sequencing (ATAC-seq) library preparation from adult Drosophila melanogaster neurons.

Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade.

The Use of <i>Drosophila</i> to Understand Psychostimulant Responses

From single flies to many genes: Using Drosophila to explore the genetics of psychostimulant consumption.

The fly liquid-food electroshock assay (FLEA) suggests opposite roles for neuropeptide F in avoidance of bitterness and shock.

The Neurotransmitters Involved in <i>Drosophila</i> Alcohol-Induced Behaviors.

Flying Together: <i>Drosophila</i> as a Tool to Understand the Genetics of Human Alcoholism

Collaborators (1)

Shin Yamazaki

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