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Çagla Tükel

Professor

Temple University

United States

Research Interests

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Professors in United States Professors in Microbiology Microbiology professors in United States

About

Çagla Tükel is an Assistant Professor at Temple University in the United States. Her research focuses on the interactions between bacterial amyloids and the host immune responses, emphasizing their roles in autoimmune and neurodegenerative diseases. Recent articles highlight her work on Salmonella enterica and the environmental factors influencing biofilm formation and dispersal.

Articles (10)

Year:

2026

Year:

2026

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Recent studies provided important insight into our understanding of the role of c-di-GMP signaling and the regulation of enteric biofilms. Despite an improved understanding of how c-di-GMP signaling regulates S. Typhimurium biofilms, the processes that affect the intracellular c-di-GMP levels and the formation of multicellular communities in vivo during infections remain unknown.

Year:

2022

Year:

2022

Collaborators (6)

Lori Rink

Associate Professor

Fox Chase Cancer Center

UNITED STATES

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Andrew Chesney

University of Oklahoma

UNITED STATES

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Ulrich H.E. Hansmann

Professor

University of Oklahoma

UNITED STATES

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Walter J. Koch

Professor

Duke University Medical Center

UNITED STATES

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Ajit Magadum

Assistant Professor

University of South Florida

UNITED STATES

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Raj Kishore

Professor and Chair

Temple University

UNITED STATES

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Çagla Tükel

Research Interests

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About

Articles (10)

Contribution of local Salmonella infection to autoreactivity: divergent roles of type I interferons in colonization and autoantibody production.

Biofilm-derived curli and Z-DNA shape anti-DNA antibody responses during Salmonella infections.

Podoplanin-positive cell-derived small extracellular vesicles contribute to cardiac amyloidosis after myocardial infarction

IUPHAR review: From gut to brain: The role of gut dysbiosis, bacterial amyloids, and metabolic disease in Alzheimer's disease

Microbiota and cancer: unraveling the significant influence of microbial communities on cancer treatment

Bacterial amyloid curli activates the host unfolded protein response via IRE1α in the presence of HLA-B27

Lactate promotes the biofilm-to-invasive-planktonic transition in Salmonella enterica serovar Typhimurium via the de novo purine pathway

The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases

Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling

Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses

Collaborators (6)

Lori Rink

Andrew Chesney

Ulrich H.E. Hansmann

Walter J. Koch

Ajit Magadum

Raj Kishore

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