Akihiro Tomida

Chief

Japan

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About

Dr. Akihiro Tomida is a Chief at the Japanese Foundation For Cancer Research in Japan. His research focuses on cancer biology, particularly the mechanisms of cell survival and resistance to therapy in melanoma and non-small cell lung cancer (NSCLC). Recent publications include studies on ferroptosis resistance, ATF4 induction during amino acid deprivation, and the effects of marine alkaloids on mutant epidermal growth factor receptors.

Articles (8)

Year:

2024

Year:

2023

Year:

2022

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2021

Year:

2021

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2020

Year:

2020

Year:

2020

Collaborators (2)

Yusuke Oku

Pharmaceuticals and Medical Devices Agency

JAPAN

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Naoyuki Nishiya

JAPAN

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Akihiro Tomida

Research Interests

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Articles (8)

Induction of stearoyl‐CoA desaturase confers cell density‐dependent ferroptosis resistance in melanoma

Activating mutations in EGFR and PI3K promote ATF4 induction for NSCLC cell survival during amino acid deprivation

Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation

Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor

eIF4B enhances ATF4 expression and contributes to cellular adaptation to asparagine limitation in BRAF-mutated A375 melanoma

Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy

GZD824 inhibits GCN2 and sensitizes cancer cells to amino acid starvation stress

The kinase PERK represses translation of the G-protein-coupled receptor LGR5 and receptor tyrosine kinase ERBB3 during ER stress in cancer cells

Collaborators (2)

Yusuke Oku

Naoyuki Nishiya

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