Akiko Takahashi

Chief

Japan

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About

Akiko Takahashi serves as the Chief at the Japanese Foundation for Cancer Research in Japan. Her research focuses on oncogene-induced senescence, extracellular vesicles, and the regulatory mechanisms of cellular aging and senescence. Recent publications highlight her contributions to the understanding of senescent markers, chromatin landscape alterations, and their implications in cancer therapies.

Articles (11)

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (3)

Mako Kamiya

Graduate School of Medicine, The University of Tokyo

JAPAN

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Hisaya Kato

Assistant Professor

Chiba University Graduate School of Medicine

JAPAN

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Noriko Yasuda

Kyushu University

JAPAN

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Akiko Takahashi

Research Interests

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Articles (11)

Dipeptidylpeptidase‐4‐targeted activatable fluorescent probes visualize senescent cells

Network of extracellular vesicles surrounding senescent cells

The discovery of oncogene-induced senescence

YBX1 Regulates Satellite II RNA Loading into Small Extracellular Vesicles and Promotes the Senescent Phenotype

Alteration in the chromatin landscape during the DNA damage response: Continuous rotation of the gear driving cellular senescence and aging

Identification of Novel Senescent Markers in Small Extracellular Vesicles

Pericentromeric repetitive ncRNA regulates chromatin interaction and inflammatory gene expression

Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.

Cancer-Specific Targeting of Taurine-Upregulated Gene 1 Enhances the Effects of Chemotherapy in Pancreatic Cancer

Senescence-associated extracellular vesicle release plays a role in senescence-associated secretory phenotype (SASP) in age-associated diseases.

Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.

Collaborators (3)

Mako Kamiya

Hisaya Kato

Noriko Yasuda

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