Akira Ishisaki

Professor

Iwate Medical University

Japan

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Akira Ishisaki is a Professor at Iwate Medical University in Japan. His research focuses on dynamic polarization of macrophages in osteonecrosis, the role of receptor tyrosine kinase ligands in fibrogenic activity, and the mechanisms of TGF-β1 in oral squamous cell carcinoma. His recent publications highlight the immunopathology associated with antiresorptive-related osteonecrosis.

Articles (4)

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (2)

Shinichiro Kuroshima

Associate Professor

Nagasaki University

JAPAN

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Masaharu Kamo

Associate Professor

Iwate Medical University

JAPAN

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Akira Ishisaki

Research Interests

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Articles (4)

Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular‑joint‑derived fibroblast‑like synoviocytes via mitogen‑activated protein kinase kinase/extracellular signal‑regulated kinase

TGF‑β1 induces N‑cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells

Dynamic polarization shifting from M1 to M2 macrophages in reduced osteonecrosis of the jaw-like lesions by cessation of anti-RANKL antibody in mice.

Distinct immunopathology in the early stages between different antiresorptives-related osteonecrosis of the jaw-like lesions in mice.

Collaborators (2)

Shinichiro Kuroshima

Masaharu Kamo

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