Akitsu Hotta

Principle Investigator, Junior Associate Professor

Japan

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About

Akitsu Hotta is a Junior Associate Professor and Principle Investigator at the Center for iPS Cell Research & Application (CiRA) at Kyoto University, Japan. His research focuses on gene therapy, stem cell biology, and the development of in vitro models for human diseases. Recent publications include studies on SARS-CoV-2 inhibition, human thymic epithelial development, and the modeling of Alport syndrome using iPSC-derived organoids.

Articles (11)

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2026

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2025

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2024

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2024

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2023

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2021

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2021

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2021

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2021

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JAPAN

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Professor

Nagoya University

JAPAN

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Akitsu Hotta

Research Interests

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About

Articles (11)

SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein

An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification

Neutralization sensitivity of SARS-CoV-2 Omicron variants FL.1 and GE.1 by therapeutic antibodies and XBB sera

Genetically engineered hypoimmunogenic cell therapy

iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model

Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells

Optimized electroporation of CRISPR-Cas9/gRNA ribonucleoprotein complex for selection-free homologous recombination in human pluripotent stem cells

Contractile Activity of Myotubes Derived from Human Induced Pluripotent Stem Cells: A Model of Duchenne Muscular Dystrophy

Efficient ssODN-Mediated Targeting by Avoiding Cellular Inhibitory RNAs through Precomplexed CRISPR-Cas9/sgRNA Ribonucleoprotein

A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs

Collaborators (9)

Yu Nakagama

Yann Pretemer

Kazutoshi Takahashi

AKATSUKI SAITO

Masamichi Kamihira

Yoshimasa Kawaguchi

Kohei Kometani

Yoshinori Kawabe

Akira Ito

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