Akiyoshi Uemura

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Professor

Nagoya University Graduate School of Medicine

Japan

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About

Akiyoshi Uemura is a Professor at Nagoya City University Graduate School of Medical Sciences in Japan. His research focuses on vascular morphogenesis, endothelial cell biology, and retinal pathologies, exploring various aspects such as metabolic reprogramming and the role of macrophages in ischemia. Recent publications highlight his investigations into the mechanical properties affecting vascular development and potential therapeutic targets for age-related diseases.

Recent Grants

Grant: Close

Mechanisms underlying endothelial cell movements and vascular patterning

Open Date: 2013-04-01

Close Date: 2016-03-01

Grant: Close

Development of therapy for diabetic macular edema

Open Date: 2013-04-01

Close Date: 2015-03-01

Grant: Close

Development of retinal vascular regeneration therapy

Open Date: 2010-04-01

Close Date: 2013-03-01

Grant: Close

Development of therapy for retinoblastoma

Open Date: 2010-04-01

Close Date: 2013-03-01

Grant: Close

Investigation of mechanisms underlying retinal angiogenesis

Open Date: 2005-04-01

Close Date: 2007-03-01

Articles (19)

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2025

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2020

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2020

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2020

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2020

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2020

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2020

Collaborators (14)

Hisako Takigawa-Imamura

Assistant Professor

Kyushu University

JAPAN

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Karis Little

Queen's University Belfast

UNITED KINGDOM

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Takashi Ushiki

Niigata University Medical and Dental Hospital

JAPAN

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Kei Sugihara

Assistant Professor

Kyushu University

JAPAN

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Sandra Ryeom

Columbia University Irving Medical Center

UNITED STATES

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Hiroyasu Kidoya

Professor

University of Fukui

JAPAN

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Dong Ho Park

Kyungpook National University

SOUTH KOREA

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Ryo Yamasaki

Kyushu University

JAPAN

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Marcus Fruttiger

University College London

UNITED KINGDOM

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Alan Stitt

The Queen's University Belfast

UNITED KINGDOM

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Harry Mellor

University of Bristol

UNITED KINGDOM

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Ryuji Yokokawa

Professor

Kyoto University

JAPAN

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Yuichiro Arima

Kumamoto University

JAPAN

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Atsuhiko IIJIMA

Professor

Niigata University

JAPAN

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Akiyoshi Uemura

Research Interests

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About

Recent Grants

Articles (19)

Biomechanical control of vascular morphogenesis by the surrounding stiffness

PDK4-mediated metabolic reprogramming is a potential therapeutic target for neovascular age-related macular degeneration

Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy

Heterotypic macrophages/microglia differentially contribute to retinal ischaemia and neovascularisation

FOXO1 stimulates tip cell-enriched gene expression in endothelial cells

Reduced chondroitin sulfate content prevents diabetic neuropathy through transforming growth factor-β signaling suppression

Analyzing the effect of cell rearrangement on Delta-Notch pattern formation

Corrigendum: PlexinD1 signaling controls domain-specific dendritic development in newborn neurons in the postnatal olfactory bulb(Front. Neurosci., (2023), 17, (1143130), 10.3389/fnins.2023.1143130)

Effect of triamcinolone acetonide on retinal inflammation and angiogenesis induced by pericyte depletion in mouse

PlexinD1 signaling controls domain-specific dendritic development in newborn neurons in the postnatal olfactory bulb

Multimodal evaluation of an interphotoreceptor retinoid-binding protein-induced mouse model of experimental autoimmune uveitis

VEGFR1 signaling in retinal angiogenesis and microinflammation

Rho GTPases in Retinal Vascular Diseases

A new perfusion culture method with a self-organized capillary network

Remodeling mechanisms determine size distributions in developing retinal vasculature

Loss of Down Syndrome Critical Region-1 Mediated-Hypercholesterolemia Accelerates Corneal Opacity Via Pathological Neovessel Formation

RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells

RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis

Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis.

Collaborators (14)

Hisako Takigawa-Imamura

Karis Little

Takashi Ushiki

Kei Sugihara

Sandra Ryeom

Hiroyasu Kidoya

Dong Ho Park

Ryo Yamasaki

Marcus Fruttiger

Alan Stitt

Harry Mellor

Ryuji Yokokawa

Yuichiro Arima

Atsuhiko IIJIMA

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