Alan J. Dickson

The University of Manchester

United Kingdom

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Articles (10)

Year:

2025

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2025

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2022

Collaborators (6)

Kate Meeson

The University of Manchester

UNITED KINGDOM

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Kathleen Cain

The University of Manchester

UNITED KINGDOM

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Susan Rosser

Professor of Synthetic Biology

University of Edinburgh

UNITED KINGDOM

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Mauro Torres

The University of Manchester

UNITED KINGDOM

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Dongda Zhang

University Lecturer

The University of Manchester

UNITED KINGDOM

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Andrew R Pitt

Aston University

UNITED KINGDOM

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Alan J. Dickson

Research Interests

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Articles (10)

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

From Discovery to Delivery

Deciphering molecular drivers of lactate metabolic shift in mammalian cell cultures

Sequence and Configuration of a Novel Bispecific Antibody Format Impacts Its Production Using Chinese Hamster Ovary (CHO) Cells

A multiscale hybrid modelling methodology for cell cultures enabled by enzyme-constrained dynamic metabolic flux analysis under uncertainty

Engineering mammalian cell growth dynamics for biomanufacturing

Long term culture promotes changes to growth, gene expression, and metabolism in CHO cells that are independent of production stability

Engineering of Chinese hamster ovary cells for co-overexpressing MYC and XBP1s increased cell proliferation and recombinant EPO production

Characterising the structural and cellular role of immunoglobulin C-terminal lysine in secretory pathways

The secretory pathway – the key for unlocking the potential of Chinese hamster ovary cell factories for manufacturing therapeutic proteins

Collaborators (6)

Kate Meeson

Kathleen Cain

Susan Rosser

Mauro Torres

Dongda Zhang

Andrew R Pitt

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