ALBERTO SERRANO-POZO

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Assistant Professor of Neurology

Massachusetts General Hospital

United States

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About

Dr. Alberto Serrano-Pozo is an Assistant Professor of Neurology at Massachusetts General Hospital. His research focuses on Alzheimer's disease and related dementias, with recent articles examining the roles of neuroinflammation and genetic factors such as APOE genotype. He employs advanced methodologies, including deep learning and transcriptomic analyses, to investigate disease heterogeneity and the molecular mechanisms underlying cognitive decline.

Recent Grants

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Mentored Career Development Award

Open Date: 2019-07-01

Close Date: 2024-04-01

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Alzheimer's Association Clinical Fellowship (AACF)

Open Date: 2017-07-01

Close Date: 2020-06-01

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R25 Educational Research Program for Neurology Residents and Fellows

Open Date: 2016-07-01

Close Date: 2018-06-01

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Pathophysiology of Alzheimer's disease

Open Date: 2010-01-01

Close Date: 2012-12-01

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Pathophysiology of Alzheimer's disease

Open Date: 2007-01-01

Close Date: 2009-12-01

Articles (15)

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2021

Collaborators (14)

Colm Cunningham

Associate Professor in Neuroscience

Trinity College Dublin

IRELAND

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Wei-Ting Chen

Head of Discovery Biology

BELGIUM

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Carole Escartin

Université Paris-Saclay

FRANCE

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Mats Nilsson

Professor

Stockholm University

SWEDEN

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Stefanie Robel

UNITED STATES

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Rosemary Jackson

Academic, Principal Investigator (Teaching and Research) - (Tenure Track)

University of Dundee

UNITED KINGDOM

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Marcela Pekna

Professor

SWEDEN

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Bradley Hyman

Professor

Harvard University

UNITED STATES

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Becky Carlyle

University of Oxford

UNITED KINGDOM

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João Filipe Oliveira

PORTUGAL

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Rebecca Betensky

NYU School of Global Public Health

UNITED STATES

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Brian MacVicar

Professor

The University of British Columbia

CANADA

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Albee Messing

University of Wisconsin-Madison

UNITED STATES

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Clara Muñoz-Castro

Universidad de Sevilla

SPAIN

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ALBERTO SERRANO-POZO

Research Interests

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About

Recent Grants

Articles (15)

Unsupervised Deep Learning of Electronic Health Records to Characterize Heterogeneity Across Alzheimer Disease and Related Dementias: Cross-Sectional Study

Interneuron diversity in the human dorsal striatum

Multifaceted roles of APOE in Alzheimer disease

Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease

Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias

Neuropathology-Independent Association BetweenAPOEGenotype and Cognitive Decline Rate in the Normal Aging-Early Alzheimer Continuum

Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease

Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment

Systematic review of human post‐mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease

Reactive astrocyte nomenclature, definitions, and future directions.

Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer’s disease

Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease

APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches

Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease (Nature Medicine, (2020), 26, 8, (1256-1263), 10.1038/s41591-020-0938-9)

Differential gene expression data from the human central nervous system across Alzheimer's disease, Lewy body diseases, and the amyotrophic lateral sclerosis and frontotemporal dementia spectrum

Collaborators (14)

Colm Cunningham

Wei-Ting Chen

Carole Escartin

Mats Nilsson

Stefanie Robel

Rosemary Jackson

Marcela Pekna

Bradley Hyman

Becky Carlyle

João Filipe Oliveira

Rebecca Betensky

Brian MacVicar

Albee Messing

Clara Muñoz-Castro

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