Alec Paschalis

Institute of Cancer Research

United Kingdom

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Articles (10)

Year:

2025

Year:

2025

Year:

2024

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2023

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2023

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2023

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2023

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2022

Year:

2022

Year:

2022

Collaborators (4)

Luke Gaughan

Reader in Molecular Oncology

Newcastle University

UNITED KINGDOM

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Mahtab Rouhifard

Institute of Cancer Research

UNITED KINGDOM

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Ram Mani

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Ian Hickson

Professor of Drug Discovery Bioscience

Newcastle University

UNITED KINGDOM

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Alec Paschalis

Research Interests

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Articles (10)

Defactinib with avutometinib in patients with solid tumors: the phase 1 FRAME trial

Treatment-related adverse events of antibody drug-conjugates in clinical trials

FRAME: A phase I trial of defactinib (FAK inhibitor) in combination with avutometinib (RAF-MEK clamp) in patients with solid tumours including low grade serous ovarian cancer

Critical role of antioxidant programs in enzalutamide-resistant prostate cancer.

The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer

Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

A Transgender Patient with Prostate Cancer: Lessons Learnt

A New Old Target: Androgen Receptor Signaling and Advanced Prostate Cancer

Prostate-Specific Membrane Antigen Expression and Response to DNA Damaging Agents in Prostate Cancer

Prostate-specific Membrane Antigen Biology in Lethal Prostate Cancer and its Therapeutic Implications

Collaborators (4)

Luke Gaughan

Mahtab Rouhifard

Ram Mani

Ian Hickson

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