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Aleksander Bilewicz

Institute of Nuclear Chemistry and Technology

Poland

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Research Interests

Medical Imaging

30%

Pharmaceutical Chemistry

40%

Nanomedicine

60%

Magnetic Nanoparticles

50%

Radiopharmaceutical Chemistry

50%

Cancer Therapy

40%

Theranostic

40%

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Articles19

Pt-Au Nanoparticles in Combination with Near-Infrared-Based Hyperthermia Increase the Temperature and Impact on the Viability and Immune Phenotype of Human Hepatocellular Carcinoma Cells

Article Link

Year:

2025

Cytotoxicity Comparison of 99mTc-Labeled Peptide Antagonist and Agonist Targeting the SSTR2 Receptor in AR42J Cells

Article Link

Year:

2025

The radioactive 103Pd and 109Pd palladium bipyridyl–bisphosphonate complexes for radionuclide therapy of bone metastatic tumor cells

Article Link

Year:

2025

Comparison of [125I]I-labeled trastuzumab and pertuzumab for targeted Auger electron therapy of cancers overexpressing HER2 receptors

Article Link

Year:

2024

Au@109Pd Core–Shell Nanoparticles Conjugated to Panitumumab for the Combined β−—Auger Electron Therapy of Triple-Negative Breast Cancer

Article Link

Year:

2024

Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers

Article Link

Year:

2023

Multimodal Radiobioconjugates of Magnetic Nanoparticles Labeled with 44Sc and 47Sc for Theranostic Application

Article Link

Year:

2023

198Au-Coated Superparamagnetic Iron Oxide Nanoparticles for Dual Magnetic Hyperthermia and Radionuclide Therapy of Hepatocellular Carcinoma

Article Link

Year:

2023

Platinum nanoparticles labelled with iodine-125 for combined “chemo-Auger electron” therapy of hepatocellular carcinoma

Article Link

Year:

2023

Challenging production of Auger electron emitter platinum-195m via double-neutron capture activation of an iridium-193 target

Article Link

Year:

2023

Au@109Pd core–shell nanoparticle conjugated to trastuzumab for the therapy of HER2+ cancers: studies on the applicability of 109Pd/109mAg in vivo generator in combined β− auger electron therapy

Article Link

Year:

2023

Multifunctional Nanoparticles Based on Iron Oxide and Gold-198 Designed for Magnetic Hyperthermia and Radionuclide Therapy as a Potential Tool for Combined HER2-Positive Cancer Treatment

Article Link

Year:

2022

Nanostructures as Radionuclide Carriers in Auger Electron Therapy

Article Link

Year:

2022

Oxidative Status as an Attribute for Selective Antitumor Activity of Platinum-Containing Nanoparticles against Hepatocellular Carcinoma

Article Link

Year:

2022

Hybrid Radiobioconjugated Superparamagnetic Iron Oxide-Based Nanoparticles for Multimodal Cancer Therapy

Article Link

Year:

2021

Au@Pt Core-Shell Nanoparticle Bioconjugates for the Therapy of HER2+ Breast Cancer and Hepatocellular Carcinoma. Model Studies on the Applicability of 193mPt and 195mPt Radionuclides in Auger Electron Therapy

Article Link

Year:

2021

Lipidic Cubic-Phase Nanoparticles (Cubosomes) Loaded with Doxorubicin and Labeled with 177Lu as a Potential Tool for Combined Chemo and Internal Radiotherapy for Cancers

Article Link

Year:

2020

Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

Article Link

Year:

2020

Design and Evaluation of 223Ra-Labeled and Anti-PSMA Targeted NaA Nanozeolites for Prostate Cancer Therapy–Part I

Article Link

Year:

2020

Collaborators10

Tomasz Ciach

Division Head, Prof.

University of Warsaw

POLAND

Agnieszka Majkowska-Pilip

Institute of Nuclear Chemistry and Technology

POLAND

Anna Lankoff

Prof

Institute of Nuclear Chemistry and Technology

POLAND

Adam Mames

Institute of Physical Chemistry, Polish Academy of Sciences

POLAND

Przemysław Koźmiński

Institute of Nuclear Chemistry and Technology

POLAND

Anna Ruszczynska

University of Warsaw

POLAND

Mateusz Wierzbicki

Associate professor

Warsaw University of Life Sciences

POLAND

Udo Gaipl

Head of Radiation Immunobiology

Universitätsklinikum Erlangen

GERMANY

Marek Pruszynski

National Centre for Nuclear Research

POLAND

Damian Gawel

dr hab. prof. CMKP

Centre of Postgraduate Medical Education

POLAND

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Aleksander Bilewicz

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Research Interests

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Articles19

Pt-Au Nanoparticles in Combination with Near-Infrared-Based Hyperthermia Increase the Temperature and Impact on the Viability and Immune Phenotype of Human Hepatocellular Carcinoma Cells

Cytotoxicity Comparison of 99mTc-Labeled Peptide Antagonist and Agonist Targeting the SSTR2 Receptor in AR42J Cells

The radioactive 103Pd and 109Pd palladium bipyridyl–bisphosphonate complexes for radionuclide therapy of bone metastatic tumor cells

Comparison of [125I]I-labeled trastuzumab and pertuzumab for targeted Auger electron therapy of cancers overexpressing HER2 receptors

Au@109Pd Core–Shell Nanoparticles Conjugated to Panitumumab for the Combined β−—Auger Electron Therapy of Triple-Negative Breast Cancer

Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers

Multimodal Radiobioconjugates of Magnetic Nanoparticles Labeled with <sup>44</sup>Sc and <sup>47</sup>Sc for Theranostic Application

<sup>198</sup>Au-Coated Superparamagnetic Iron Oxide Nanoparticles for Dual Magnetic Hyperthermia and Radionuclide Therapy of Hepatocellular Carcinoma

Platinum nanoparticles labelled with iodine-125 for combined “chemo-Auger electron” therapy of hepatocellular carcinoma

Challenging production of Auger electron emitter platinum-195m via double-neutron capture activation of an iridium-193 target

Au@109Pd core–shell nanoparticle conjugated to trastuzumab for the therapy of HER2+ cancers: studies on the applicability of 109Pd/109mAg in vivo generator in combined β− auger electron therapy

Multifunctional Nanoparticles Based on Iron Oxide and Gold-198 Designed for Magnetic Hyperthermia and Radionuclide Therapy as a Potential Tool for Combined HER2-Positive Cancer Treatment

Nanostructures as Radionuclide Carriers in Auger Electron Therapy

Oxidative Status as an Attribute for Selective Antitumor Activity of Platinum-Containing Nanoparticles against Hepatocellular Carcinoma

Hybrid Radiobioconjugated Superparamagnetic Iron Oxide-Based Nanoparticles for Multimodal Cancer Therapy

Au@Pt Core-Shell Nanoparticle Bioconjugates for the Therapy of HER2+ Breast Cancer and Hepatocellular Carcinoma. Model Studies on the Applicability of <sup>193m</sup>Pt and <sup>195m</sup>Pt Radionuclides in Auger Electron Therapy

Lipidic Cubic-Phase Nanoparticles (Cubosomes) Loaded with Doxorubicin and Labeled with <sup>177</sup>Lu as a Potential Tool for Combined Chemo and Internal Radiotherapy for Cancers

Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

Design and Evaluation of <sup>223</sup>Ra-Labeled and Anti-PSMA Targeted NaA Nanozeolites for Prostate Cancer Therapy–Part I

Collaborators10

Tomasz Ciach

Agnieszka Majkowska-Pilip

Anna Lankoff

Adam Mames

Przemysław Koźmiński

Anna Ruszczynska

Mateusz Wierzbicki

Udo Gaipl

Marek Pruszynski

Damian Gawel

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