Ales Marek

Institute of Organic Chemistry and Biochemistry

Czech Republic

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Articles (17)

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (5)

Gabriela Nováková

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Lenka Zakova

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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František Tureček

University of Washington

UNITED STATES

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Tommy Johansen

Københavns Universitet

DENMARK

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Milos Hroch

Associate professor

Charles University in Prague, Faculty of Medicine in Hradec Kralove

CZECH REPUBLIC

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Ales Marek

Research Interests

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Articles (17)

Nucleoside Cation Radicals: Generation, Radical-Induced Hydrogen Atom Migrations, and Ribose Ring Cleavage in the Gas Phase

Direct Multi‐Deuterium Labelling of Pirtobrutinib

Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand

Synthesis of [3H]Org24598 using in‐house prepared [3H]MeI

Competitive Radical Migrations and Ribose Ring Cleavage in Adenosine and 2′-Deoxyadenosine Cation Radicals

The DNA Radical Code. Resolution of Identity in Dissociations of Trinucleotide Codon Cation Radicals in the Gas Phase

Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation

GPR160 is not a receptor of anorexigenic cocaine- and amphetamine-regulated transcript peptide

Resolution of Identity in Gas-Phase Dissociations of Mono- and Diprotonated DNA Trinucleotide Codons by 15N-Labeling and Computational Structure Analysis

Low‐scale syringe‐made synthesis of 15N‐labeled oligonucleotides

Synthesis of N‐acetyl‐l‐aspartyl‐l‐glutamic acid; [3H]NAAG

Tritium hydrogen‐isotope exchange with electron‐poor tertiary benzenesulfonamide moiety; application in late‐stage labeling of T0901317

Synthesis of [<sup>13</sup> C<sub>6</sub> ]-Ibrutinib.

Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats

Charge-Tagged Nucleosides in the Gas Phase: UV–Vis Action Spectroscopy and Structures of Cytidine Cations, Dications, and Cation Radicals

A radioligand receptor binding assay for measuring of insulin secreted by MIN6 cells after stimulation with glucose, arginine, ornithine, dopamine, and serotonin

Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

Collaborators (5)

Gabriela Nováková

Lenka Zakova

František Tureček

Tommy Johansen

Milos Hroch

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