ALESSANDRA BALDUINI

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Full Professor

University of Pavia

Italy

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About

Alessandra Balduini is a Full Professor at the University of Pavia, Italy. Her research interests encompass megakaryocyte culture, platelet biology, and the molecular mechanisms underlying multiple myeloma and thrombocytopenia. She is actively involved in advancing techniques for ex vivo production of blood cells and seeks to unveil the genetic factors related to platelet disorders. Her recent publications reflect a commitment to understanding the interactions within the bone marrow microenvironment and the pathogenesis of hematological conditions.

Recent Grants

Grant: Close

Development of an in vitro viability and tumorigenicity index for genome-edited hHSPCs with the MOAB bioreactor

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

Characterization of the hematopoietic niche under physiological and stress conditions by the use of microfluidic bioreactors and engineered red blood cells

Open Date: 2019-01-01

Close Date: 2023-01-01

Grant: Close

Fibronectin isoforms: new regulators of fibrosis progression in myeloproliferative neoplasms

Open Date: 2017-01-01

Close Date: 2022-01-01

Grant: Close

Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research

Open Date: 2017-01-01

Close Date: 2022-01-01

Articles (10)

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Collaborators (5)

ALESSANDRO MALARA

Associate Professor

Università degli Studi di Pavia

ITALY

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Vittorio Abbonante

Assistant Professor (Ricercatore a t. determinato SSD BIO/12)

Università degli Studi Magna Graecia di Catanzaro Dipartimento di Scienze della Salute

ITALY

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Marco Castelli

University of Verona

ITALY

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ALESSANDRO PECCI

ITALY

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Christian Andrea DI BUDUO

Assistant Professor

University of Pavia

ITALY

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ALESSANDRA BALDUINI

Research Interests

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About

Recent Grants

Articles (10)

Low penetrance COL5A1 variants in a young patient with intracranial aneurysm and very mild signs of Ehlers-Danlos syndrome

Megakaryocyte Cytoskeletal Proteins in Platelet Biogenesis and Diseases

A Gold Standard Protocol for Human Megakaryocyte Culture Based on the Analysis of 1,500 Umbilical Cord Blood Samples

Expression and functional characterization of the large-conductance calcium and voltage-activated potassium channel K<inf>ca</inf>1.1 in megakaryocytes and platelets

Halting the vicious cycle within the multiple myeloma ecosystem: Blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Latest culture techniques: Cracking the secrets of bone marrow to mass-produce erythrocytes and platelets ex vivo

Miniaturized 3d bone marrow tissue model to assess response to thrombopoietin-receptor agonists in patients

Pathogenetic and clinical study of a patient with thrombocytopenia due to the p.E527K gain-of-function variant of SRC

iPSC diversity: A key for better use and improved targeting

Collaborators (5)

ALESSANDRO MALARA

Vittorio Abbonante

Marco Castelli

ALESSANDRO PECCI

Christian Andrea DI BUDUO

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