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Alessandra Pontillo

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Associated Professor (Professor Associado)

University of Sao Paulo

Brazil

Research Interests

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Professors in Immunology

Recent Grants

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Evaluation of Inflammasome Activation in Cells of Patients with Autoinflammatory Disease and Its Correlation with Individual Genetics

Open Date: 2024-08-01

Close Date: 2026-07-01

Grant: Close

MODULATOR EFFECT OF TORID ON THE PATHOLOGICAL ACTIVATION OF INFLAMMASOME: A GENETIC-BASED APPROACH

Open Date: 2019-01-01

Close Date: 2021-01-01

Grant: Close

Contribution of inflammasome in multiple sclerosis pathogenesis

Open Date: 2017-12-01

Close Date: 2019-11-01

Grant: Close

CHARACTERIZATION OF NOVEL MOLECULAR PLAYERS IN THE CONTROL OF OBESITY AND OBESITY-INDUCED INFLAMMATION

Open Date: 2017-11-01

Close Date: 2019-10-01

Grant: Close

Immunogenetics of the inflammasome and translational study "from bed to bench and back": analysis of variations in inflammasome genes in monogenic and multifactorial autoinflammatory diseases for differential diagnosis and therapeutic applications.

Open Date: 2016-07-01

Close Date: 2018-06-01

Articles (14)

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2023

Collaborators (1)

Helder Nakaya

Associate Professor

University of Sao Paulo

BRAZIL

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Alessandra Pontillo

Research Interests

Explore related searches

Recent Grants

Articles (14)

An NLRP3 Variant Protects Against Severe COVID-19: An Unexpected Contribution of Inflammasome Genetics in SARS-CoV-2 Infection

Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants

Transcriptomic and Immunopathological Profiles of Inflammasomes in Different Clinical Forms of American Cutaneous Leishmaniasis

Analysis of Complement Factor H gene polymorphisms and their association with clinical manifestations ofleptospirosis

Bruton's tyrosine kinase (BTK) and matrix metalloproteinase-9 (MMP-9) regulate NLRP3 inflammasome-dependent cytokine and neutrophil extracellular trap responses in primary neutrophils

Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp.

Integrated Genetic and Cellular Analysis Reveals NLRP1 Activation in CD4+ T Lymphocytes During Chronic HIV Infection

Role of C–C chemokine receptor type 5 in pathogenesis of malaria and its severe forms

Unexplained fever with consumptive syndrome in the elderly: two cases of VEXAS syndrome with inflammasome dysregulation

A common variant close to the “tripwire” linker region of NLRP1 contributes to severe COVID-19

Canonical Inflammasomes

Cervical carcinoma induces NLRP3 inflammasome activation and IL-1ß release in human peripheral blood monocytes affecting patients’ overall survival

Severe COVID-19 patients show a dysregulation of the NLRP3 inflammasome in circulating neutrophils

The Ala134Thr variant in TMEM176B exerts a beneficial role in colorectal cancer prognosis by increasing NLRP3 inflammasome activation

Collaborators (1)

Helder Nakaya

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