Alessandro Arcovito

Associate Professor

Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia

Italy

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About

Alessandro Arcovito is an Associate Professor at Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia in Italy. His research focuses on innovative drug delivery systems, particularly utilizing nanocarriers such as recombinant human ferritin and PLGA-based nanoparticles for targeted therapies in various medical conditions. Recent publications highlight his work on personalized treatments for genetic disorders and advancements in drug repurposing strategies for lysosomal diseases.

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2025

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2020

Collaborators (21)

Elisabetta Tabolacci

Catholic University of the Sacred Heart

ITALY

Alessandro Arcovito

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Articles (24)

Targeting Glucosylceramide Synthase: Innovative Drug Repurposing Strategies for Lysosomal Diseases

Development of an Innovative Dual Construct for Targeted Drug Delivery in the Oral Cavity

A first-in-class non-cytotoxic nanocarrier based on a recombinant human ferritin boosts targeted therapy, chemotherapy and immunotherapy.

Targeted allele-specific FGFR2 knockdown via human recombinant ferritin nanoparticles for personalized treatment of Crouzon syndrome

PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2

Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate

Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model

New Insight into the genotype-phenotype correlation of PTH1R variants and primary failure of tooth eruption on an Italian Cohort

Functionalized PLGA-Based Nanoparticles with Anti-HSV-2 Human Monoclonal Antibody: A Proof of Concept for Early Diagnosis and Targeted Therapy

Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary

Human Glucosylceramide Synthase at Work as Provided by “In Silico” Molecular Docking, Molecular Dynamics, and Metadynamics

Cinnamaldehyde Loaded Poly(lactide-co-glycolide) (PLGA) Microparticles for Antifungal Delivery Application against Resistant Candida albicans and Candida glabrata

Oral Mucosa Models to Evaluate Drug Permeability

Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein

3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity

Cellulosic Textiles—An Appealing Trend for Different Pharmaceutical Applications

Mother and Daughter Carrying of the Same Pathogenic Variant in FGFR2 with Discordant Phenotype

Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells

Personalized Bone Reconstruction and Regeneration in the Treatment of Craniosynostosis

Novel Mixed NOP/Opioid Receptor Peptide Agonists

Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene

Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins

Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis

Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy

Collaborators (21)

Elisabetta Tabolacci

Angelo Toto

Maurizio Sanguinetti

serena rinaldo

Valentina Loconte

Eliano Cascardi

Daniela Palacios

Carlo Lajolo

giuseppina nocca

Francesca Bugli

Cristina GRIPPAUDO

Pietro Chiurazzi

Virginia Cristofori

Chiara Massera

CONSTANTINOS ATHANASSOPOULOS

Alessandro Casnati

Serena Brundu

Carla Boccaccio

cristina limatola

Ilaria Cacciotti

Giulia Franzolin

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