Alessandro Sette

Professor and Member

La Jolla Institute for Immunology

United States

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About

Professor Alessandro Sette is a member of the La Jolla Institute for Immunology in the United States. His research primarily focuses on T-cell responses to various pathogens, including Mycobacterium tuberculosis, Bordetella pertussis, and SARS-CoV-2. He has contributed to the understanding of immune responses in vaccine development and the characterization of immune responses in infectious diseases such as Monkeypox and chikungunya. His work aims to enhance the efficacy of vaccination strategies and to unravel the complexities of the human immune system.

Alessandro Sette

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Articles (18)

Human CD4+ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses

Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop

Targets of influenza human T-cell response are mostly conserved in H5N1

Booster Vaccination with BNT162b2 Improves Cellular and Humoral Immune Response in the Pediatric Population Immunized with CoronaVac

Characterization of the Monkeypox Virus [MPX]-Specific Immune Response in MPX-Cured Individuals Using Whole Blood to Monitor Memory Response

T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and Numerous SARS-CoV-2-Specific CD4- CD8- Double Negative T Cells and Regulatory T Cells

Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing

A measles virus-based vaccine induces robust chikungunya virus-specific CD4+ T-cell responses in a phase II clinical trial

A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps

CD4<sup>+</sup> T Cell Responses to <i>Toxoplasma gondii</i> Are a Double-Edged Sword

Stimulation of Potent Humoral and Cellular Immunity via Synthetic Dual-Antigen MVA-Based COVID-19 Vaccine COH04S1 in Cancer Patients Post Hematopoietic Cell Transplantation and Cellular Therapy

The Importance of Measuring SARS-CoV-2-Specific T-Cell Responses in an Ongoing Pandemic

Characterization of the immune impairment of patients with tuberculosis and COVID-19 coinfection

Imprinting of Gut-Homing Receptors on Mtb-Specific Th1* Cells Is Associated with Reduced Lung Homing after Gavage BCG Vaccination of Rhesus Macaques

Metabolic dysregulation impairs lymphocyte function during severe SARS-CoV-2 infection

Virus-Specific Stem Cell Memory CD8+ T Cells May Indicate a Long-Term Protection against Evolving SARS-CoV-2

Correction: Correlative CD4 and CD8 T-cell immunodominance in humans and mice: implications for preclinical testing

Evaluation of Cross-Immunity to the Mpox Virus Due to Historic Smallpox Vaccination

Collaborators (11)

Rik De Swart

emanuele nicastri

Massimo Francalancia

Rory Dylan de Vries

Stephen Carpenter

Flavia Chiuppesi

Jun-ichi Abe

Saeid Najafi-Fard

Hannah Carter

Bjoern Peters

Daniela Weiskopf

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