Alessia Finotti

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Assistant Professor

University of Ferrara

Italy

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About

Alessia Finotti is an Assistant Professor at the University of Ferrara, Italy. Her research focuses on bioactive molecules related to garlic extract, microRNA therapeutics for cystic fibrosis, and the genetic implications of β-thalassemia. Recent articles by Professor Finotti explore therapeutic strategies for mitigating the effects of smoking, enhancing stem cell differentiation, and the molecular effects of the SARS-CoV-2 spike protein. She is actively involved in advancing research that has critical implications for patient management in hematological disorders.

Recent Grants

Grant: Close

Biosensori e nuove piattaforme tecnologiche per la biopsia liquida e l'indagine di miRNA circolanti

Open Date: 2017-01-01

Close Date: 2017-01-01

Grant: Close

MicroRNA profiling in biopsie liquide di pazienti con Sindrome di Shwachman-Diamond: identificazione delle basi molecolari della patologia e di nuovi markers prognostici

Open Date: 2016-11-01

Close Date: 2017-12-01

Grant: Close

Novel molecular biomarkers for detection of autologous blood transfusion in sport: fetal hemoglobin and microRNAs

Open Date: 2015-01-01

Close Date: 2016-01-01

Grant: Close

TRPA1 channels as novel molecular targets for anti-inflammatory therapies in CF lung

Open Date: 2014-09-01

Close Date: 2016-08-01

Articles (20)

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University of Ferrara

UNITED STATES

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Monica Borgatti

Associate Professor in Biochemistry

University of Ferrara

ITALY

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Jan Traeger-Synodinos

Professor (currently)

National and Kapodistrian University of Athens - Faculty of Medicine

GREECE

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Alessia Finotti

Research Interests

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About

Recent Grants

Articles (20)

Secretome Release During In Vitro Bone Marrow-Derived Mesenchymal Stem Cell Differentiation Induced by Bio-Oss® Collagen Material

Aged Garlic Extract and Its Bioactive Molecules S-Allyl-Cysteine and S1-Propenyl-Cysteine: A Review Focusing on Evidences Supporting Their Use for Mitigating the Effects of Cigarette Smoking

Perspectives in MicroRNA Therapeutics for Cystic Fibrosis

A β-Thalassemia Cell Biobank: Updates, Further Validation in Genetic and Therapeutic Research and Opportunities During (and After) the COVID-19 Pandemic

Therapeutic Relevance of Inducing Autophagy in β-Thalassemia

Increased Expression of α-Hemoglobin Stabilizing Protein (AHSP) mRNA in Erythroid Precursor Cells Isolated from β-Thalassemia Patients Treated with Sirolimus (Rapamycin)

Impact of α-Globin Gene Expression and α-Globin Modifiers on the Phenotype of β-Thalassemia and Other Hemoglobinopathies: Implications for Patient Management

Aged Garlic Extract (AGE) and Its Constituent S-Allyl-Cysteine (SAC) Inhibit the Expression of Pro-Inflammatory Genes Induced in Bronchial Epithelial IB3-1 Cells by Exposure to the SARS-CoV-2 Spike Protein and the BNT162b2 Vaccine

Inhibitory effects of SARS-CoV-2 spike protein and BNT162b2 vaccine on erythropoietin-induced globin gene expression in erythroid precursor cells from patients with β-thalassemia

Cationic Calix[4]arene Vectors to Efficiently Deliver AntimiRNA Peptide Nucleic Acids (PNAs) and miRNA Mimics

The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathies

Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers

Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221-3p and miR-222-3p: Synergistic Effects on Apoptosis

Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study

The Cystic Fibrosis Transmembrane Conductance Regulator Gene (CFTR) Is under Post-Transcriptional Control of microRNAs: Analysis of the Effects of agomiRNAs Mimicking miR-145-5p, miR-101-3p, and miR-335-5p

New Synthetic Isoxazole Derivatives Acting as Potent Inducers of Fetal Hemoglobin in Erythroid Precursor Cells Isolated from β-Thalassemic Patients

MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines

Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin

Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene

Collaborators (14)

Alex Manicardi

Roberto Gambari

Alberto Macone

Roberto Corradini

Elisa Mazzoni

Nicoletta Bianchi

Christalena Sofocleous

Ilaria Lampronti

Laura Gambari

giovanni marzaro

Alessandro Casnati

Gianni Sacchetti

Monica Borgatti

Jan Traeger-Synodinos

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