Alexa Pichet Binette

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Assistant professor

Université de Montréal

Canada

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About

Dr. Alexa Pichet Binette is an Assistant Professor at Université de Montréal, Canada. Her research focuses on Alzheimer's disease, particularly the predictive value of plasma biomarkers and the relationship between tau pathology, amyloid deposition, and cognitive impairment. Recent publications explore the effects of aging and the APOE4 gene on cognitive function, as well as the associations between neurophysiology and disease progression in older adults.

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Grant: Close

Characterization of tau pathology heterogeneity across the Alzheimer’s disease spectrum

Open Date: 2021-07-01

Close Date: 2023-09-30

Articles (10)

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2025

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2023

Collaborators (6)

Tammie Benzinger

Professor

Washington University in St. Louis

UNITED STATES

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Alex Wiesman

Assistant Professor

Simon Fraser University

CANADA

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Larissa Fischer

University of California, Irvine

UNITED STATES

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Sandhitsu Das

Research Assistant Professor

University of Pennsylvania

UNITED STATES

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Niklas Mattsson-Carlgren

PI, Associate Professor

Lund University

SWEDEN

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Danielle van Westen

Lund University

SWEDEN

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Alexa Pichet Binette

Research Interests

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Contact this professor

About

Recent Grants

Articles (10)

Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults

Precuneus Activity during Retrieval Is Positively Associated with Amyloid Burden in Cognitively Normal Older APOE4 Carriers

Predictive Value of Plasma Biomarkers in Tau‐PET Transitions

Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer’s Disease

Tau, atrophy, and domain‐specific cognitive impairment in typical Alzheimer's disease

Associations between misfolded alpha‐synuclein aggregates and Alzheimer's disease pathology in vivo

Synergistic association of Aβ and tau pathology with cortical neurophysiology and cognitive decline in asymptomatic older adults

Proteomic changes in Alzheimer’s disease associated with progressive Aβ plaque and tau tangle pathologies

Disease staging of Alzheimer’s disease using a CSF-based biomarker model

Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance

Collaborators (6)

Tammie Benzinger

Alex Wiesman

Larissa Fischer

Sandhitsu Das

Niklas Mattsson-Carlgren

Danielle van Westen

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