Alexander Andrianov

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Research Professor

United States

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About

Dr. Alexander Andrianov is a Research Professor at the University of Maryland, IBBR, in the United States. His research focuses on advanced polymeric systems, particularly in the development and characterization of polyphosphazene-based materials for biomedical applications. His recent articles explore topics such as polymer nanoparticle systems, protein-polyelectrolyte interactions, and innovative delivery methods for vaccine antigens.

Recent Grants

Grant: Close

Collaborative Research: Conformal Assemblies of Polyphosphazenes with Controlled Biofuncationality

Open Date: 2018-07-15

Close Date: 2021-06-30

Grant: Close

Novel Polyphosphazene Technology for Stabilizing Protein Therapeutics

Open Date: 2017-06-01

Close Date: 2018-03-01

Grant: Close

Structure-Based Vaccine Design for Hepatits C Virus

Open Date: 2017-06-01

Close Date: 2022-05-31

Grant: Close

Polyphosphazene Presenters for the Mulitmeric Protein Malaria Vaccine

Open Date: 2003-10-01

Close Date: 2004-09-30

Grant: Close

Development of an Intranasal Rotavirus Subunit Vaccine

Open Date: 2002-07-15

Close Date: 2003-03-14

Articles (18)

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2022

Collaborators (7)

Chang-Hwan Choi

Professor

Stevens Institute of Technology

UNITED STATES

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Junho Moon

Texas A&M University

UNITED STATES

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Thomas R. Fuerst

UNITED STATES

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Svetlana A. Sukhishvili

UNITED STATES

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Beverly Ellis

Scripps Research Institute

UNITED STATES

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Michael Lueckheide

Assistant Professor

Adelphi University

UNITED STATES

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Mark R. Prausnitz

UNITED STATES

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Alexander Andrianov

Research Interests

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About

Recent Grants

Articles (18)

Cyclic Macromolecular Chains Visualized by Cryo-EM and AFM Reveal a Ring Expansion Polymerization Mechanism in a Classical Synthetic Pathway to Polyphosphazenes

Polyphosphazene-Mediated Assembly of TLR4 and TLR7/8 Agonists Enables a Potent Nano-Adjuvant Delivery System for Hepatitis C Virus Vaccine Antigens

Virus-Mimicking Polymer Nanocomplexes Co-Assembling HCV E1E2 and Core Proteins with TLR 7/8 Agonist—Synthesis, Characterization, and In Vivo Activity

Protein–polyelectrolyte complexation: effects of sterically repulsive groups, macromolecular architecture and hierarchical assembly

Engineering Degradation Rate of Polyphosphazene-Based Layer-by-Layer Polymer Coatings

Directly visualizing individual polyorganophosphazenes and their single-chain complexes with proteins

Immunopotentiating Polyphosphazene Delivery Systems: Supramolecular Self-Assembly and Stability in the Presence of Plasma Proteins

Hydrolytically Degradable Zwitterionic Polyphosphazene Containing HEPES Moieties as Side Groups

Noncovalent PEGylation of protein and peptide therapeutics

Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine

Fluorine-Functionalized Polyphosphazene Immunoadjuvant: Synthesis, Solution Behavior and In Vivo Potency

4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity

Monitoring Protein Complexation with Polyphosphazene Polyelectrolyte Using Automated Dynamic Light Scattering Titration and Asymmetric Flow Field Flow Fractionation and Protein Recognition Immunoassay

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

Factors Controlling Degradation of Biologically Relevant Synthetic Polymers in Solution and Solid State

Supramolecular Protein-Polyelectrolyte Assembly at Near Physiological Conditions—Water Proton NMR, ITC, and DLS Study

Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development

Hierarchically Structured, All-Aqueous-Coated Hydrophobic Surfaces with pH-Selective Droplet Transfer Capability

Collaborators (7)

Chang-Hwan Choi

Junho Moon

Thomas R. Fuerst

Svetlana A. Sukhishvili

Beverly Ellis

Michael Lueckheide

Mark R. Prausnitz

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