Alexander G. Obukhov

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Associate Professor of Anatomy, Cell Biology & Physiology

Indiana University School of Medicine

United States

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Recent Grants

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Mechanisms of endothelial dysfunction in traumatic brain injury

Open Date: 2017-07-01

Close Date: 2021-06-01

Grant: Close

TRPC Channels in the Metabolic Syndrome

Open Date: 2012-07-01

Close Date: 2017-05-31

Grant: Close

Molecular Physiology of TRPC Channels

Open Date: 2006-12-04

Close Date: 2013-06-30

Grant: Close

Function and regulation of voltage-independent, calcium-permeable TRPC4 and TRPC5 channels in adrenal chromaffin cells

Open Date: 2003-07-01

Close Date: 2007-06-01

Articles (20)

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2020

Collaborators (5)

Kenji Mizuguchi

Osaka University

JAPAN

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Fletcher White

Professor

Indiana University School of Medicine

UNITED STATES

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Md Ruhul Amin

Assistant Professor

University of Chicago

UNITED STATES

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Takashi Hato

Indiana State University

UNITED STATES

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Jagdish C Joshi

Research Assistant Professor

University of Chicago

UNITED STATES

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Alexander G. Obukhov

Research Interests

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Recent Grants

Articles (20)

Pharmacological targeting of adaptor proteins in chronic inflammation.

In vitro and in vivo inhibition of the host TRPC4 channel attenuates Zika virus infection.

Investigating the potential of natural compounds and known drugs against obstructive airway inflammation in inhibiting TRPC6

Basal ATP release signals through the P2Y<sub>2</sub> receptor to maintain the differentiated phenotype of vascular smooth muscle cells.

An improved mouse model of sepsis based on intraperitoneal injections of the enriched culture of cecum slurry.

Effect of reactive oxygen, nitrogen, and sulfur species on signaling pathways in atherosclerosis.

Structural and accessibility studies highlight the differential binding of clemizole to TRPC5 and TRPC6.

The fate of drug discovery in academia; dumping in the publication landfill?

Long-Term Treatment with Gadopentetic Acid or Gadodiamide Increases TRPC5 Expression and Decreases Adriamycin Nuclear Accumulation in Breast Cancer Cells

Dihydroceramides Derived from Bacteroidetes Species Sensitize TRPV1 Channels

Novel peptide inhibitors targeting CD40 and CD40L interaction: A potential for atherosclerosis therapy.

Propranolol treatment during repetitive mild traumatic brain injuries induces transcriptomic changes in the bone marrow of mice.

Human microRNA (miR-20b-5p) modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer's biomarkers.

Capsaicin and TRPV1 Channels in the Cardiovascular System: The Role of Inflammation

Transient Receptor Potential Canonical Channels in Health and Disease: A 2020 Update

The Potential Role of Osteopontin and Furin in Worsening Disease Outcomes in COVID-19 Patients with Pre-Existing Diabetes

SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes

Transient Receptor Potential Canonical (TRPC) Channels: Then and Now

ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.

Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE.

Collaborators (5)

Kenji Mizuguchi

Fletcher White

Md Ruhul Amin

Takashi Hato

Jagdish C Joshi

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