Alexander Krah

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Singapore

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Professors in Molecular Biology

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Ｆ型ＡＴＰ合成酵素のＦＩ複合体の構造、機能および選択性

Open Date: 2013-04-01

Close Date: 2015-03-31

Articles (15)

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2025

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2024

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2020

Collaborators (5)

Duncan G. G. McMillan

Delft University of Technology

NETHERLANDS

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Richard Henchman

Senior Lecturer

The University of Manchester

UNITED KINGDOM

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Peter J. Bond

National University of Singapore (NUS)

SINGAPORE

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Roderick W. Bates

Nanyang Technological University (NTU)

SINGAPORE

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Yasuhisa Kimura

Associate Professor

Kyoto University

JAPAN

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Alexander Krah

Research Interests

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Recent Grants

Articles (15)

Water occupancy in the Acinetobacter baumannii F-ATP synthase c-ring and its implications as a novel inhibitor target

Coarse-Grained Model of Glycosaminoglycans for Biomolecular Simulations

Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors

High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo

Variations of the Mycobacterium abscessus F-ATP synthase subunit a-c interface alter binding and potency of the anti-TB drug bedaquiline

Observation of multiple protein temperature transitions dependent upon the chemical environment

ATP binding by an F1Fo ATP synthase ε subunit is pH dependent, suggesting a diversity of ε subunit functional regulation in bacteria

Binding properties of the anti-TB drugs bedaquiline and TBAJ-876 to a mycobacterial F-ATP synthase

Bridging the N-terminal and middle domains in FliG of the flagellar rotor

A second shell residue modulates a conserved ATP-binding site with radically different affinities for ATP

Extending the Martini Coarse-Grained Force Field to N-Glycans

An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit

The Molecular Basis for Purine Binding Selectivity in the Bacterial ATP Synthase ϵ Subunit

Characterizing the Hydration Properties of Proton Binding Sites in the ATP Synthase c-Rings of Bacillus Species

How ligand binding affects the dynamical transition temperature in proteins

Collaborators (5)

Duncan G. G. McMillan

Richard Henchman

Peter J. Bond

Roderick W. Bates

Yasuhisa Kimura

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