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Alexandra K. Kiemer

Professor of Pharmaceutical Biology

Saarland University

Germany

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Alexandra K. Kiemer is a Professor of Pharmaceutical Biology at Saarland University in Germany. Her research focuses on cancer biology, specifically the vulnerabilities of PLK1-overexpressing cancers, gene editing, and anti-cancer drug targets. Additionally, she investigates the role of extracellular vesicles in cancer progression and wound healing, as well as the epigenetic alterations in liver diseases.

Articles (18)

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2025

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2022

Collaborators (11)

Marc Schneider

Head of Biopharmaceutics and Pharmaceutical Technology

Saarland University

GERMANY

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Nicole Ludwig

Saarland University

GERMANY

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Michael Kohlstedt

Saarland University

GERMANY

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Gregor Fuhrmann

Chair for Pharmaceutical Biology

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Matthias Engel

Saarland University

GERMANY

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Anne Hecksteden

Leopold-Franzens-Universität Innsbruck

AUSTRIA

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Robert K. Gieseler

University Hospital

GERMANY

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Ranjan Kumar Maji

Goethe University Frankfurt

GERMANY

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Arefeh Kardani

Saarland University

GERMANY

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Rudolf Schicho

Associate Professor

Medical University of Graz

AUSTRIA

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Emmanuel Ampofo

Saarland University

GERMANY

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Alexandra K. Kiemer

Research Interests

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About

Articles (18)

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

Laminar Flow Alters EV Composition in HUVECs: A Study of Culture Medium Optimization and Molecular Profiling of Vesicle Cargo

Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target

A cell-free, biomimetic hydrogel based on probiotic membrane vesicles ameliorates wound healing

C-Myc/H19/miR-29b axis downregulates nerve/glial (NG)2 expression in glioblastoma multiforme

Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function

The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages

Nanostructured Microparticles Repolarize Macrophages and Induce Cell Death in an In Vitro Model of Tumour-Associated Macrophages

Cell‐Derived Vesicles for Antibiotic Delivery—Understanding the Challenges of a Biogenic Carrier System

A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.

Control of CAR-T cell activity in space and time: the next level of anti-tumor action

Endotoxin Tolerance Acquisition and Altered Hepatic Fatty Acid Profile in Aged Mice

Alterations in the hepatocyte epigenetic landscape in steatosis

Characterization of Anti-Cancer Activities of Violacein: Actions on Tumor Cells and the Tumor Microenvironment

Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA

Kupffer cells are protective in alcoholic steatosis

Nano‐in‐Microparticles for Aerosol Delivery of Antibiotic‐Loaded, Fucose‐Derivatized, and Macrophage‐Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery

Spray-dried pneumococcal membrane vesicles are promising candidates for pulmonary immunization

Collaborators (11)

Marc Schneider

Nicole Ludwig

Michael Kohlstedt

Gregor Fuhrmann

Matthias Engel

Anne Hecksteden

Robert K. Gieseler

Ranjan Kumar Maji

Arefeh Kardani

Rudolf Schicho

Emmanuel Ampofo

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