Alexandra Kovach

Director, Hematopathology; Associate Professor, Keck School of Medicine of University of Southern California

Children's Hospital of Los Angeles

United States

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About

Dr. Alexandra Kovach serves as the Director of Hematopathology and an Associate Professor at the Keck School of Medicine of the University of Southern California, based at Children's Hospital Los Angeles, USA. Her research focuses on pediatric hematologic malignancies, particularly in the areas of post-immunotherapy relapses, genomic landscapes of leukemias, and advancements in CAR-T cell therapies. Recent publications include insights into durable remission in acute myeloid leukemia and the complex genetic alterations associated with B-lymphoblastic leukemia.

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2020

Collaborators (2)

Lauren Reiman

Professional Research Assistant

University of Colorado Anschutz Medical Campus

UNITED STATES

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Michele S. Redell

Baylor College of Medicine

UNITED STATES

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Alexandra Kovach

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Articles (20)

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Achievement of durable remission of relapsed/refractory acute myeloid leukemia in a child using venetoclax monotherapy

Genomic landscape of testicular follicular lymphoma is characterized by frequent 1p36/TNFRSF14 alterations

CD33–CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells

Pediatric therapy-related hematologic neoplasms show enrichment for KMT2A rearrangement and lymphoblastic phenotype

A de novo germline RUNX1 variant preceding development of concurrent T-lymphoblastic leukemia and myelodysplastic syndrome

How I treat post-immunotherapy relapsed B-ALL

IKZF1PLUS alterations contribute to outcome disparities in Hispanic/Latino children with B‐lymphoblastic leukemia

Concordance of Next-Generation Sequencing and Multiparametric Flow Cytometry Methods for Detecting Measurable Residual Disease in Adult Acute Lymphoblastic Leukemia: Optimizing Prediction of Clinical Outcomes From a Single-Center Study

Maturational dyssynchrony in benign B‐cell precursors following lymphocyte depleting chemotherapy: A potential pitfall for B‐lymphoblastic leukemia minimal/measurable residual disease (MRD) flow cytometry analysis

An Exome Capture-Based RNA-Sequencing Assay for Genome-Wide Identification and Prioritization of Clinically Important Fusions in Pediatric Tumors

Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells

Updates on lymphoblastic leukemia/lymphoma classification and minimal/measurable residual disease analysis

Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL

Primary sinonasal large B cell lymphoma is as histopathologically heterogeneous as systemic large B cell lymphoma but may show subtype-specific tropism for specific sinonasal anatomic sites

Update on Pediatric and Young Adult Mature Lymphomas.

Optical genome mapping detects rare genetic drivers in pediatric B-lymphoblastic leukemia

Pediatric hematolymphoid pathology in the gastrointestinal tract.

Low-grade Appendiceal Mucinous Neoplasm and Endometriosis: Incidental Coincident Pathologies at Cesarean Section.

Pediatric Aggressive Mature B-Cell Lymphomas, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

Collaborators (2)

Lauren Reiman

Michele S. Redell

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