Alexandra Trkola

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University of Zurich

Switzerland

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Recent Grants

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Understanding HIV-1 broadly neutralizing antibody evolution - The Swiss 4.5K Screen

Open Date: 2017-04-01

Close Date: 2021-03-31

Grant: Close

Transmission of influenza virus from asymptomatic healthcare workers and inpatients in the acute care hospital setting: A prospective study over two consecutive influenza seasons

Open Date: 2015-05-01

Close Date: 2019-04-30

Grant: Close

The role of humoral immunity in HIV infection - Understanding broadly neutralizing antibody evolution

Open Date: 2014-04-01

Close Date: 2017-03-31

Grant: Close

The role of humoral immunity in HIV infection

Open Date: 2011-04-01

Close Date: 2014-03-31

Grant: Close

HIV-envelope-specific DARPin-based microbicide strategies

Open Date: 2009-09-15

Close Date: 2014-08-31

Articles (19)

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Collaborators (18)

Michael Huber

Head Diagnostics and Development

University of Zurich

SWITZERLAND

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C.T. Berger

SWITZERLAND

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Andreas Plate

University Hospital of Zurich

SWITZERLAND

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Roger D Kouyos

University Hospital of Zurich

SWITZERLAND

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Katharina Kusejko

University of Zurich

SWITZERLAND

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Irene Abela

University of Zurich

SWITZERLAND

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Antonia Maria Susanne Müller

Department Chair, Professor of Cellular Therapies and Transfusion Medicine

Medical University of Vienna

AUSTRIA

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Patrick Ernst

Head Faculty Affairs

University of Zurich

SWITZERLAND

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Anthony Hauser

SWITZERLAND

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Matthias Cavassini

SWITZERLAND

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Lukas Fenner

University of Bern

SWITZERLAND

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Julia Notter

University Hospital Basel

SWITZERLAND

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Niklaus D Labhardt

University Hospital Basel

SWITZERLAND

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Pierre-Yves Bochud

Associate Professor

Centre Hospitalier Universitaire Vaudois

SWITZERLAND

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Jennifer A Brown

University Hospital Basel

SWITZERLAND

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Philip TARR

SWITZERLAND

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Claus Kadelka

Assistant Professor

Iowa State University

UNITED STATES

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Nikolas Friedrich

University of Zurich

SWITZERLAND

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Alexandra Trkola

Research Interests

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Recent Grants

Articles (19)

Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection

Deciphering Factors Linked With Reduced Severe Acute Respiratory Syndrome Coronavirus 2 Susceptibility in the Swiss HIV Cohort Study

Impact of hormonal therapy on HIV‐1 immune markers in cis women and gender minorities

ART-DEX: A novel strategy to monitor broadly neutralizing antibody activity during antiretroviral therapy of HIV-1

Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines.

Antibody and T-cell response to bivalent booster SARS-CoV-2 vaccines in people with compromised immune function (COVERALL-3).

Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic.

How much should we sequence? An analysis of the Swiss SARS-CoV-2 surveillance effort.

Seroprofiling of Antibodies Against Endemic Human Coronaviruses and Severe Acute Respiratory Syndrome Coronavirus 2 in a Human Immunodeficiency Virus Cohort in Lesotho: Correlates of Antibody Response and Seropositivity

Bridging the Gap: identifying factors impacting mRNA SARS-CoV-2 vaccine booster response in people living with HIV-1.

Antibody Response to SARS-CoV-2 Vaccination in Patients following Allogeneic Hematopoietic Cell Transplantation.

Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial.

Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV.

Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response.

Alpha variant coronavirus outbreak in a nursing home despite high vaccination coverage: molecular, epidemiological and immunological studies.

Cohort Profile Update: The Swiss HIV Cohort Study (SHCS).

Comparison of analytical sensitivity and efficiency for SARS-CoV-2 primer sets by TaqMan-based and SYBR Green-based RT-qPCR.

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

Single-Chain Variable Fragments of Broadly Neutralizing Antibodies Prevent HIV Cell-Cell Transmission.

Collaborators (18)

Michael Huber

C.T. Berger

Andreas Plate

Roger D Kouyos

Katharina Kusejko

Irene Abela

Antonia Maria Susanne Müller

Patrick Ernst

Anthony Hauser

Matthias Cavassini

Lukas Fenner

Julia Notter

Niklaus D Labhardt

Pierre-Yves Bochud

Jennifer A Brown

Philip TARR

Claus Kadelka

Nikolas Friedrich

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