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Alexandre Hinzpeter

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Scientist

INSERM

France

Research Interests

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Professors in France Professors in Biochemistry Biochemistry professors in France

Recent Grants

Grant: Open

STABTHER

Open Date: 2024-01-01

Close Date: 2027-01-01

Grant: Close

TACTIC

Open Date: 2023-01-01

Close Date: 2026-01-01

Grant: Close

Study of the CFTR surface interactom

Open Date: 2022-03-01

Close Date: 2025-03-01

Grant: Close

Inclusion strategy for CFTR exons carrying mutations within the acceptor splice site

Open Date: 2020-10-01

Close Date: 2021-12-01

Grant: Close

Influence of the non-coding 3'UTR on the degradation by NMD of transcripts carrying premature stop codons.

Open Date: 2019-10-01

Close Date: 2020-06-01

Articles (11)

Year:

2026

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2025

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2025

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2025

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2024

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2024

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2024

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2024

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2023

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2023

Year:

2023

Collaborators (6)

Maria Miteva

Research Director at Inserm

INSERM

FRANCE

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patrick balaguer

FRANCE

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Miroslaw Zajac

Assistant Professor

Warsaw University of Life Sciences

POLAND

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Pierre-Régis Burgel

Assistance Publique - Hôpitaux de Paris

FRANCE

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Flora Zavala

Directeur de Recherche Emérite

CNRS Délégation Paris B

FRANCE

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Isabelle Callebaut

Sorbonne Université

FRANCE

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Alexandre Hinzpeter

Research Interests

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Recent Grants

Articles (11)

Spray-Pyrolyzed Hollow and Yolk–Shell CeO2 Nanocarriers with Tunable Structure for Redox-Responsive Delivery and Gene Rescue Applications

CFTR correctors potentiate gating mutants causing cystic fibrosis.

Beyond Trikafta: new models to assess tissue dependent rescue of N1303K-CFTR.

In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators.

ATP-Binding Cassette and Solute Carrier Transporters: Understanding Their Mechanisms and Drug Modulation Through Structural and Modeling Approaches

Novel gain-of-function mutants identify a critical region within CFTR membrane-spanning domain 2 controlling cAMP-dependent and ATP-independent channel activation.

The expanded French compassionate programme for elexacaftor-tezacaftor-ivacaftor use in people with cystic fibrosis without a F508del CFTR variant: a real-world study.

TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR.

Theratyping Cystic Fibrosis patients to guide Elexacaftor-Tezacaftor-Ivacaftor out of label prescription

Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

Nonsense mutations accelerate lung disease and decrease survival of cystic fibrosis children.

Collaborators (6)

Maria Miteva

patrick balaguer

Miroslaw Zajac

Pierre-Régis Burgel

Flora Zavala

Isabelle Callebaut

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